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Takeda Pharmaceutical · Boston, MA

Senior Director, Medicinal Chemistry

Boston, Massachusetts, United StatesFull-timeDirector{'@type': 'MonetaryAmount', 'currency': 'USD', 'value': {'@type': 'QuantitativeValue', 'minValue': 212000, 'maxValue': 333190, 'unitText': ''}}Research & Science

Listed on Takeda Pharmaceutical’s official careers site. Posted October 30, 2026. Check that it is still open and apply there.

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Job description

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use . I further attest that all information I submit in my employment application is true to the best of my knowledge.

Job Description

About the role: We are seeking an experienced leader to join the Global Chemistry Leadership Team as Senior Director of Medicinal Chemistry. In this role, the successful candidate will provide strategic guidance and oversight for our medicinal chemistry efforts. Drawing on deep drug-hunting expertise, they will help shape chemistry strategy and portfolio decisions, and ensure alignment with company priorities. They will also oversee medicinal chemistry projects conducted at contract research organizations (CROs), with accountability for their execution and progression.

How you will contribute

Leadership and Strategy: Provide strategic leadership and oversight to the medicinal chemistry department, aligned with company strategy and priorities.

Project Management

Oversee the design, execution, and management of medicinal chemistry projects conducted at CROs, ensuring timely progress and high-quality outcomes, including vendor performance, budget, data integrity, and IP protection.

Team Development

Mentor and develop a team of internal chemists, fostering a collaborative and innovative work environment.

Collaboration

Partner closely with cross-functional teams, including biology, pharmacology, and clinical development, to advance drug candidates from discovery through development.

Innovation

Drive innovation in medicinal chemistry through the integration of new technologies, methodologies, and best practices.

External Partnerships

Build and maintain relationships with external partners, including academic institutions, industry collaborators, and CROs.

Business Development

Identify and create external opportunities that meet the strategic scientific, therapeutic, and commercial needs of the organization Qualifications: Expected education and experience: PhD degree in Chemistry, Medicinal Chemistry, or a related discipline, with 15+ years experience, or MS with 21+ years experience, or BS with 23+ years experience Proven track record of leading drug discovery programs that have delivered clinical candidates.

Leadership Skills

Experience leading and developing high-performing teams.

Technical Expertise

Deep understanding of medicinal chemistry principles, project execution, and drug design.

Communication

Excellent verbal and written communication skills, with the ability to explain complex scientific concepts to a broad audience.

CRO Management

Experience managing external CRO partners for medicinal chemistry programs, including vendor oversight, budget and resource management, and data quality, ideally across multiple regions and time zones.

Problem-Solving

Strong analytical and problem-solving skills, with a proactive and innovative approach to challenges.

Adaptability

Ability to adapt to changing priorities and make sound decisions with incomplete or evolving data. This position is currently classified as “hybrid” in accordance with Takeda’s Hybrid and Remote Work policy. Takeda Compensation and Benefits Summary We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.

For Location

Boston, MA U.S.

Base Salary Range

$212,000.00 - $333,190.00 The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job.

The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. For information about our benefits, please click here . EEO Statement Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Locations Boston, MA Worker Type Employee Worker Sub-Type Regular Time Type Full time Job Exempt Yes It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

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