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Takeda Pharmaceutical

Senior Director, Global Medicinal Chemistry (Shonan, Japan)

DirectorResearch & Science

Listed on Takeda Pharmaceutical’s official careers site. Listed as of October 18, 2026. Check that it is still open and apply there.

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Job description

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use . I further attest that all information I submit in my employment application is true to the best of my knowledge.

Job Description

Objective / Purpose: We are seeking a seasoned and visionary Senior Director of Medicinal Chemistry to join our leadership team. This individual will play a pivotal role in shaping the future direction of our company by providing strategic guidance and oversight to our medicinal chemistry efforts. The ideal candidate will be instrumental in driving our drug discovery initiatives forward, ensuring their successful progression and alignment with our company's overall goals and objectives.

By leveraging their expertise, they will significantly influence our strategic decisions and contribute to the advancement of our scientific and commercial endeavors. Additionally, this person will oversee external programs at CROs, managing the design, execution, and progression of medicinal chemistry projects conducted exclusively at these organizations Accountabilities: Create business development opportunities that meet the strategic scientific, therapeutic, and commercial needs of the organization or specific Therapeutic Area (TA).

Leadership and Strategy

Provide strategic leadership and oversight to the medicinal chemistry department, aligning with the company's overall goals and objectives.

Project Management

Oversee the design, execution, and management of medicinal chemistry projects conducted exclusively at CROs, ensuring timely progress and high-quality outcomes.

Team Development

Mentor and develop a team of internal chemists, fostering a collaborative and innovative work environment.

Collaboration

Work closely with cross-functional teams, including biology, pharmacology, and clinical development, to advance drug candidates from discovery through development.

Innovation

Drive innovation in medicinal chemistry through the integration of new technologies, methodologies, and best practices.

Regulatory Compliance

Ensure all activities comply with relevant regulatory requirements and industry standards.

External Partnerships

Build and maintain relationships with external partners, including academic institutions, industry collaborators, and contract research organizations.

Education & Competencies (Technical and Behavioral)

Expected education and experience: PhD degree in Chemistry, Medicinal Chemistry or related discipline with 15+ years experience in small molecule projects. Proven track record of leading successful drug discovery programs, preferably in large pharma.

Leadership Skills

Strong leadership and managerial skills with experience leading and developing high-performing teams.

Technical Expertise

Deep understanding of medicinal chemistry principles, drug design, and optimization processes.

Communication

Excellent verbal and written communication skills, with the ability to effectively communicate complex scientific concepts to a broad audience.

Problem-Solving

Strong analytical and problem-solving skills, with a proactive and innovative approach to challenges.

Collaboration

Proven ability to work collaboratively in a cross-functional team environment.

Adaptability

Ability to adapt to changing priorities and work effectively in a fast-paced and dynamic environment.

Preferred Qualifications

Experience: Experience in a leadership role within a large pharmaceutical or biotechnology company is highly desirable. A proven track record of leading projects that are completely outsourced Publications: A strong publication record in medicinal chemistry or related fields.

Patents

Experience with patent filings and intellectual property management.

Networking

Established network within the scientific and pharmaceutical community.

Takeda Compensation and Benefits Summary

Allowances: Commutation, Housing, Overtime Work etc.

Salary Increase

Annually, Bonus Payment: Twice a year Working Hours: Headquarters (Osaka/ Tokyo) 9:00-17:30, Production Sites (Osaka/ Yamaguchi) 8:00-16:45, (Narita) 8:30-17:15, Research Site (Kanagawa) 9:00-17:45 Holidays: Saturdays, Sundays, National Holidays, May Day, Year-End Holidays etc. (approx. 123 days in a year)

Paid Leaves

Annual Paid Leave, Special Paid Leave, Sick Leave, Family Support Leave, Maternity Leave, Childcare Leave, Family Nursing Leave.

Flexible Work Styles

Flextime, Telework Benefits: Social Insurance, Retirement and Corporate Pension, Employee Stock Ownership Program, etc.

Important Notice concerning working conditions

It is possible the job scope may change at the company’s discretion. It is possible the department and workplace may change at the company’s discretion. Locations Fujisawa, Japan Worker Type Employee Worker Sub-Type Regular Time Type Full time

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