生物学助理总监

Job description

岗位职责

1）作为项目负责人带领团队开展新药研发项目，涵盖从靶点选择到临床前候选化合物（PCC）确定； 2）带领团队开展大分子、小分子及ADC等创新药物的体外筛选与评估工作； 3）负责创新药物的分子、细胞水平和疾病模型筛选平台的建立，以及筛选项目的方案设计、验证和优化； 4）领导相关疾病靶点（肿瘤/免疫/代谢性疾病/心血管疾病等）的调研工作并形成总结报告，以及进行相关项目的立项工作； 5）负责方案设计、资源协调，以及跨部门合作推进项目进展直至PCC交付。

Responsibilities

• Serve as the project lead for new drug R&D projects, covering stages from target selection to the identification of preclinical candidates (PCC).
• Lead the team in conducting in vitro screening and evaluation of innovative drugs, including biologics, small molecules, and ADCs.
• Establish in vitro screening platforms at the molecular and cellular levels for innovative drugs, and design, validate, and optimize screening project plans.
• Lead the research on relevant disease targets (including but not limited to oncology, immunology, metabolic diseases, and cardiovascular diseases), produce summary reports, and drive the initiation of related projects..
• Design project plans, coordinate resources, and collaborate with various departments to advance projects until PCC delivery.

岗位要求

1）分子生物学、细胞生物学、药理学、抗体工程、基因工程、免疫学、生物技术等相关方向全日制博士学历，第一学历为985院校或同等水平院校者优先，具有海外知名院校或研究机构的学习/工作经验者优先； 2）取得最高学位后具有5-10年以上创新药物研发经验和3年以上团队管理经验，熟悉临床前研发全流程，具有2个以上成功推进PCC阶段的项目经验； 3）对前沿生物学技术具有一定的了解和掌握，如基因微扰、酶学、分子生物学、细胞生物学和临床前动物模型等； 4）具备优秀的科研规划、项目管理和跨部门协调能力，能够高效推进多线程研发任务； 5）工作积极主动、求知欲强，有良好的组织能力者优先，有良好的人际交往能力者优先。

Qualifications

• PhD in Molecular Biology, Cell Biology, Pharmacology, Antibody Engineering, Genetic Engineering, Immunology, Biotechnology, or a related field. Candidates with a bachelor’s degree from a 985 Project university or equivalent institution are preferred. Those with study or work experience at internationally renowned universities or research institutes are also preferred.
• At least 5-10 years of experience in innovative drug R&D and over 3 years of team management experience. Familiar with the full preclinical R&D process, with experience in successfully advancing at least 2 projects to the PCC stage.
• Knowledge and practical understanding of cutting-edge biological technologies, such as genetic perturbation, enzymology, molecular biology, cell biology, and preclinical animal models.
• Strong capabilities in scientific planning, project management, and cross-departmental coordination, with the ability to efficiently advance multiple parallel R&D tasks.
• Proactive, intellectually curious, and eager to learn. Strong organizational and interpersonal skills are preferred.