[Skip to main content](#main-content) [OpenNash Jobs](https://jobs.opennash.com/) [Hiring report](/reports/hiring/) · [All Vertex Pharmaceuticals jobs](https://jobs.opennash.com/companies/vertex-pharmaceuticals/) · [Search jobs](/search/) Vertex Pharmaceuticals · Boston, MA # Clinical Development Senior Medical Director-Neurology Boston, MA Director $280,600 - $420,800 Healthcare & Clinical Listed on Vertex Pharmaceuticals’s official careers site. Listed as of October 18, 2026. Check that it is still open and apply there. [Apply on Vertex Pharmaceuticals’s careers site →](https://vrtx.wd501.myworkdayjobs.com/vertex_careers/job/Boston-MA/Clinical-Development-Senior-Medical-Director-Neurology_REQ-28764) [OpenNash Jobs](https://jobs.opennash.com/) / [Vertex Pharmaceuticals](https://jobs.opennash.com/companies/vertex-pharmaceuticals/) / Clinical Development Senior Medical Director-Neurology ## Job description ### Job Description General Summary: The Senior Medical Director will define the clinical development strategy of an asset, work with cross-functional multidisciplinary teams to define overall asset strategy as well as clinical trials strategy, design and execution, and may serve as the Medical Lead for clinical trials that will be conducted with these compounds. ### Key Duties and Responsibilities - Defines a clinical development strategy and prepare the clinical development plans, in conjunction with other relevant functional areas - Participates in the development of study protocols, statistical analysis plans, investigator's brochures, and other key study documents in conjunction with other line functions and with minimal guidance - Leads the Project Team, and works with cross-functional team members to define a project strategy and ensure execution against approved strategy - Participates in the preparation of regulatory documents in support of regulatory submissions, including clinical section of INDs and CTAs, safety reports, responses to regulatory authorities, clinical study reports, and other documents as appropriate Interfaces with regulatory authorities as appropriate - Monitors and/or oversees medical monitoring of clinical studies - Participates in business development and strategic planning activities - Acts as liaison between clinical development and other internal groups at Vertex for assigned studies - Provides medical and development leadership for cross-functional teams - Serves on cross-functional study teams for assigned trials, working with other team members to achieve efficient, high-quality study execution, and data analysis - Represents Vertex to outside medical personal in the development of clinical protocols and study conduct - Knowledge and Skills: Global clinical research experience, and experience interacting with regulatory authorities is highly desired - Ability to work collaboratively in a fast-paced, team-based matrix environment - Ability to work independently to resolve challenges Enterprise-wide thinking and ability to work in ambiguity - Ability to ensure the completeness of team work - Excellent oral and written communication skills Board certification/eligibility in a specialty is highly desired Education and Experience: MD, DO or equivalent ex-US medical degree Board certification/eligibility in a specialty is highly desired Typically requires - 12 years Pharmaceutical/Biotech industry experience, including time managing clinical trials and clinical development programs, or the equivalent combination of education and experience #LI-JM1 Pay Range: $280,600 - $420,800 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. ### Flex Designation Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status: In this Hybrid-Eligible role, you can choose to be designated as: 1. ### Hybrid work remotely up to two days per week; or select 2. ### On-Site work five days per week on-site with ad hoc flexibility. ### Note The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time. #LI-Hybrid Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com ## At a glance - Posted by the employer: Not stated - First seen by OpenNash: Jul 11, 2026 - Last checked: Oct 18, 2026 - Listed for: 99 days - Location: Boston, MA - Pay: $280,600 - $420,800[Apply on Vertex Pharmaceuticals’s careers site →](https://vrtx.wd501.myworkdayjobs.com/vertex_careers/job/Boston-MA/Clinical-Development-Senior-Medical-Director-Neurology_REQ-28764) ## More jobs at Vertex Pharmaceuticals ### [Associate Director Medical Writing (Hybrid)](https://jobs.opennash.com/companies/vertex-pharmaceuticals/jobs/dad39d8f82d9a5d0e605/) Boston, MA ### [Associate Director, Clinical Study Quality Lead (Hybrid)](https://jobs.opennash.com/companies/vertex-pharmaceuticals/jobs/91762bbfca6ff5d00990/) Boston, MA ### [Associate Director, Nonclinical Development Program Management & Strategic Operations (Late-Stage Development)](https://jobs.opennash.com/companies/vertex-pharmaceuticals/jobs/e8eea97ac4a6e51e1274/) Boston, MA ### [Business Engagement & Technology, Associate Director - Clinical & Early Development](https://jobs.opennash.com/companies/vertex-pharmaceuticals/jobs/9f22e33949444753dce5/) Boston, MA ### [Clinical Development Associate Medical Director- gMG](https://jobs.opennash.com/companies/vertex-pharmaceuticals/jobs/03bb04ec6bd1f44b4a08/) Boston, MA ## Similar jobs at other companies ### [Medical Director, Clinical Development – MRD Portfolio (Solid Tumors)](https://jobs.opennash.com/companies/labcorp-holdings/jobs/13e9c00eba28f9adc238/) Labcorp Holdings · Durham, North Carolina, United States of America ### [Global Development Medical Director, Late Respiratory and Immunology Clinical Development](https://jobs.opennash.com/companies/astrazeneca/jobs/ac926ad7be40ab9df066/) AstraZeneca · Boston, Massachusetts ### [Senior Director, Clinical Development](https://jobs.opennash.com/companies/daiichi-sankyo/jobs/bd57db4345a57068afa5/) Daiichi Sankyo · Basking Ridge, NJ, USA ### [Medical Director, Clinical Development, Allergy & Immunology](https://jobs.opennash.com/companies/regeneron-pharmaceuticals/jobs/260a29ab73dd77410da5/) Regeneron Pharmaceuticals · Tarrytown OpenNash lists jobs from employers’ own careers sites and does not handle applications. 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