[Skip to main content](#main-content) [OpenNash Jobs](https://jobs.opennash.com/) [Hiring report](/reports/hiring/) · [All Vertex Pharmaceuticals jobs](https://jobs.opennash.com/companies/vertex-pharmaceuticals/) · [Search jobs](/search/) Vertex Pharmaceuticals · Boston, MA # Senior Director, Human Resources Business Partner, Global Commercial Strategy Boston, MA Director $227,200 - $340,800 HR & Recruiting Listed on Vertex Pharmaceuticals’s official careers site. Listed as of October 18, 2026. Check that it is still open and apply there. [Apply on Vertex Pharmaceuticals’s careers site →](https://vrtx.wd501.myworkdayjobs.com/vertex_careers/job/Boston-MA/Senior-Director--Human-Resources-Business-Partner--Global-Commercial-Strategy_REQ-29429-1) [OpenNash Jobs](https://jobs.opennash.com/) / [Vertex Pharmaceuticals](https://jobs.opennash.com/companies/vertex-pharmaceuticals/) / Senior Director, Human Resources Business Partner, Global Commercial Strategy ## Job description ### Role Summary The Senior Director, Human Resources Business Partner (HRBP) provides strategic HR partnership to leaders across Global Commercial Strategy, U.S. Pricing & Access / Government Affairs, Global Pricing, and Health Economics & Outcomes Research (HEOR). Reporting to the Head of HR for Commercialization, this role focuses on talent strategy, organizational design, and supporting commercial transformation efforts. This role partners closely with the VP of Commercial Transformation to align people and organizational priorities with the broader Commercial Transformation agenda, and in support of the resources within the transformation office. ### Key Responsibilities HR Business Partnership - Serve as a strategic HR advisor to senior leaders across multiple Commercialization functions - Provide guidance on organization design, talent management, and workforce planning - Support leaders in aligning people strategies to business priorities ### Commercial Transformation Support - Partner with Commercial Transformation leadership to support execution of transformation initiatives - Translate business priorities into organizational and talent implications - Support implementation of new operating models and ways of working ### Talent Strategy - Support identification and assessment of critical roles across Commercialization - Partner with Talent and business leaders on succession planning and development strategies - Contribute to capability-building and commercial excellence initiatives ### Organizational Effectiveness & Change - Support organizational design and change initiatives across supported functions - Provide coaching and guidance to leaders during periods of change - Use data and insights to inform talent and organization decisions ### HR Delivery Model - Partner with a shared People Advisor who supports employee relations, performance management processes, and day‑to‑day HR needs - Ensure alignment between strategic priorities and HR program execution Qualifications 10–12+ years of HR experience, including HR Business - Partner roles in complex, matrixed organizations Experience supporting commercial, pricing, access, strategy, or value functions preferred Experience in organizational design, talent management, and change initiatives - Strong business acumen and ability to influence senior stakeholders Pay Range: $227,200 - $340,800 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. ### Flex Designation Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status: In this Hybrid-Eligible role, you can choose to be designated as: 1. ### Hybrid work remotely up to two days per week; or select 2. ### On-Site work five days per week on-site with ad hoc flexibility. ### Note The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time. #LI-Hybrid Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com ## At a glance - Posted by the employer: Not stated - First seen by OpenNash: Jul 11, 2026 - Last checked: Oct 18, 2026 - Listed for: 99 days - Location: Boston, MA - Pay: $227,200 - $340,800[Apply on Vertex Pharmaceuticals’s careers site →](https://vrtx.wd501.myworkdayjobs.com/vertex_careers/job/Boston-MA/Senior-Director--Human-Resources-Business-Partner--Global-Commercial-Strategy_REQ-29429-1) ## More jobs at Vertex Pharmaceuticals ### [Human Resources Business Partner Senior Director](https://jobs.opennash.com/companies/vertex-pharmaceuticals/jobs/77cdca63f705856d2af8/) Boston, MA ### [Spring 2027 Co-op, Business Process Excellence, HR Transformation](https://jobs.opennash.com/companies/vertex-pharmaceuticals/jobs/f7fb06f6904ace52861c/) Boston, MA ### [2027 MBA Summer Associate - Commercial](https://jobs.opennash.com/companies/vertex-pharmaceuticals/jobs/f5abe1585bd9334138c6/) Boston, MA ### [2027 MBA Summer Associate - Finance](https://jobs.opennash.com/companies/vertex-pharmaceuticals/jobs/3d7a09c5f0fb0abdc9ae/) Boston, MA ### [Accounting Manager - Treasury](https://jobs.opennash.com/companies/vertex-pharmaceuticals/jobs/1da8546c14216ec62fa9/) Boston, MA ## Similar jobs at other companies ### [Human Resources Director, Business Lead - Global Water](https://jobs.opennash.com/companies/ecolab/jobs/2d17b4e042f293c6da90/) Ecolab · Naperville, Illinois, United States of America ### [Human Resources Business Partner](https://jobs.opennash.com/companies/eaton/jobs/1423bc69f648b4e2836d/) Eaton · Davenport, Iowa, USA ### [Senior Human Resources Business Partner](https://jobs.opennash.com/companies/sgs/jobs/8352f719e3e9ba2ad87a/) SGS · Lincolnshire, IL, United States ### [Senior Human Resources Business Partner](https://jobs.opennash.com/companies/sgs/jobs/1e72364bc6e27270eed7/) SGS · Richardson, TX, United States ### [Human Resources Director](https://jobs.opennash.com/companies/comfort-systems-usa/jobs/3361cbff4035f1ed9ef1/) Comfort Systems USA · Grand Rapids, MI OpenNash lists jobs from employers’ own careers sites and does not handle applications. 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