[Skip to main content](#main-content) [OpenNash Jobs](https://jobs.opennash.com/) [Hiring report](/reports/hiring/) · [All Stryker jobs](https://jobs.opennash.com/companies/stryker/) · [Search jobs](/search/) Stryker · Multiple locations # Principal Engineer, Systems Engineering Multiple locations Senior individual contributor $118,000 - $196,700 Operations Listed on Stryker’s official careers site. Posted September 22, 2026. Check that it is still open and apply there. [Apply on Stryker’s careers site →](https://stryker.wd1.myworkdayjobs.com/StrykerCareers/job/Portage-Michigan/Principal-Engineer--Systems-Engineering_R573168) [OpenNash Jobs](https://jobs.opennash.com/) / [Stryker](https://jobs.opennash.com/companies/stryker/) / Principal Engineer, Systems Engineering ## Job description ### Work Flexibility Hybrid or Onsite Stryker is seeking a dynamic and visionary product development leader with a proven track record of leading large, complex product development programs through the application of systems engineering principles. As the technical quarterback, this individual will drive alignment, collaboration, and execution across a multidisciplinary global product line, ensuring teams work cohesively toward shared objectives while delivering innovative solutions that improve patient care. As medical technologies continue to evolve, our products must operate seamlessly within broader healthcare ecosystems and enabling technology platforms. This leader will be responsible for defining and overseeing system-level architectures, ensuring robust integration across hardware, software, data, connectivity, and partner technologies. They will champion a systems-thinking approach, proactively identify opportunities and risks, and ensuring our products deliver a seamless user experience while supporting the future needs of a connected healthcare environment. The ideal candidate combines deep technical expertise with exceptional leadership, influencing stakeholders across functions, geographies, and organizational levels to bring complex systems and product visions to life. [https://www.stryker.com/us/en/nse.html](https://www.stryker.com/us/en/nse.html) ### What You Will Do Lead system architecture, technical strategy, and integration activities for complex medical device products and platforms. Translate customer, clinical, and business needs into system-level requirements and drive alignment across software, electrical, and mechanical engineering teams. Lead requirements development, allocation, traceability, and verification planning throughout the product lifecycle. Drive system-level decision making, architecture reviews, tradeoff analyses, and risk assessments. Lead cross-functional product development efforts from concept through verification, ensuring delivery of safe, reliable, and high-quality solutions. Partner with Quality, Regulatory, Clinical, and Engineering stakeholders to ensure compliance with design controls and applicable standards. Identify, assess, and mitigate product development risks while promoting a risk-based development approach. Evaluate emerging technologies and recommend new capabilities, platforms, and solutions that support future customer needs. Build alignment across global stakeholders and influence design direction without direct authority. What You Will Need (Required Qualifications) Bachelor’s degree in Systems, Electrical, Mechanical, Software, Biomedical Engineering, or a related engineering discipline. 8+ years of relevant engineering experience in product development, systems engineering, or technical leadership roles. Experience developing products within a regulated industry environment. ### Preferred Qualifications Medical device product development experience. Experience leading system architecture and integration activities for complex, multidisciplinary products. Knowledge of requirements management, verification, and system-level risk management. Experience with ISO 13485, ISO 14971, FDA Design Controls, or similar regulatory frameworks. Experience with requirements management tools such as Jama, DOORS, or Polarion. Experience with Model-Based Systems Engineering (MBSE) and SysML. Experience developing connected products, digital health solutions, or integrated healthcare technologies. Experience mentoring engineers and leading design efforts across cross-functional teams. $118,000 - $196,700 USD Annual Travel Percentage: 20% Stryker Corporation is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex, gender identity, sexual orientation, national origin, disability, or protected veteran status. Stryker is an EO employer – M/F/Veteran/Disability. Stryker Corporation will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay or the pay of another employee or applicant. However, employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information, unless the disclosure is (a) in response to a formal complaint or charge, (b) in furtherance of an investigation, proceeding, hearing, or action, including an investigation conducted by the employer, or (c) consistent with the contractor’s legal duty to furnish information. ## At a glance - Posted by the employer: Sep 22, 2026 - First seen by OpenNash: Oct 11, 2026 - Last checked: Oct 18, 2026 - Listed for: 26 days - Location: Multiple locations - Pay: $118,000 - $196,700[Apply on Stryker’s careers site →](https://stryker.wd1.myworkdayjobs.com/StrykerCareers/job/Portage-Michigan/Principal-Engineer--Systems-Engineering_R573168) ## More jobs at Stryker ### [Engineer, FORGE (Future Operations Leaders Growth and Excellence) Program](https://jobs.opennash.com/companies/stryker/jobs/0cf56f363d4d61ac01c2/) ### [Operations Manager - KSA & UAE](https://jobs.opennash.com/companies/stryker/jobs/e2f019ca76311476ceee/) ### [Senior Test Engineer (Onsite)- Test Lab](https://jobs.opennash.com/companies/stryker/jobs/e97bbf7b5677ba0f7b4f/) ### [Sr. Systems Business Architect (hybrid)](https://jobs.opennash.com/companies/stryker/jobs/c288740edfa49a341569/) ### [Staff Engineer, Advanced Operations (AO)](https://jobs.opennash.com/companies/stryker/jobs/c274cc9a768e8a7a750a/) ## Similar jobs at other companies ### [Principal Engineer - AI Platform (Forward Deployed Engineering and AI Builder Experience)](https://jobs.opennash.com/companies/target/jobs/eadcf3a806eee029b0ac/) Target ### [Principal Manufacturing Systems Engineer/Sr. Principal Manufacturing Systems Engineer](https://jobs.opennash.com/companies/northrop-grumman/jobs/df788fdd4942a862eff7/) Northrop Grumman ### [Principal Systems Engineer / Sr. Principal Systems Engineer - Data Analyst](https://jobs.opennash.com/companies/northrop-grumman/jobs/8ba14ddbcf0e4d808b5e/) Northrop Grumman ### [Principal Engineer - HVDC Systems Engineering (M/D/F)](https://jobs.opennash.com/companies/ge-vernova/jobs/e4312fb7231e8886281a/) GE Vernova ### [Principal Power Systems Engineer](https://jobs.opennash.com/companies/ntt/jobs/2571f20eca7d249d0719/) NTT · London, United Kingdom [Operations jobs](/functions/operations/) OpenNash lists jobs from employers’ own careers sites and does not handle applications. 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