[Skip to main content](#main-content) [OpenNash Jobs](https://jobs.opennash.com/) [Hiring report](/reports/hiring/) · [All Roche Holding jobs](https://jobs.opennash.com/companies/roche-holding/) · [Search jobs](/search/) Roche Holding · Santa Clara # Senior Bioinformatics Software Engineer Santa Clara Full-time Senior individual contributor $145,300-$269,800 Software Engineering Listed on Roche Holding’s official careers site. Listed as of October 18, 2026. Check that it is still open and apply there. [Apply on Roche Holding’s careers site →](https://roche.wd3.myworkdayjobs.com/roche-ext/job/Santa-Clara/Senior-Bioinformatics-Software-Engineer_202607-118174-2) [OpenNash Jobs](https://jobs.opennash.com/) / [Roche Holding](https://jobs.opennash.com/companies/roche-holding/) / Senior Bioinformatics Software Engineer ## Job description At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters. The Position The Opportunity As a Bioinformatics Software Engineer, you will design, develop, and implement features for the bioinformatics components and pipelines that are used in Roche Sequencing products. You will be part of a team working in a fast paced environment, developing cutting-edge, distributed, scale-out Next-Generation Sequencing data analysis software to ensure the highest possible software quality for gene sequencing research and disease diagnostics. Work closely with experimental teams to understand their requirements and translate them into functional software, implementing those solutions directly within an existing research code repository. Collaborate with research and algorithm experts, accelerating bioinformatics techniques using GPU hardware. You will navigate and contribute to a large code base, applying your knowledge of advanced bioinformatics techniques (such as alignment methods and other sequence analysis algorithms) and neural nets to continuously improve the quality and feature sets of the software products. ### Who You Are B.S. or M.S. or PhD in Computational Biology or Bioinformatics or Biomedical engineering or related field. 5+ years of experience in working with NGS data and data analysis pipelines. Strong expertise in Python, including numerical computing and data science libraries, alongside familiarity with C/C++. Demonstrated experience developing, maintaining, or refactoring within a large code base or existing research code repository. Understanding of core bioinformatics techniques, including alignment methods, as well as neural nets. Experience collaborating with experimental teams to gather requirements and implement technical solutions. Thrives in a fast paced environment, showing a self-driven, detail oriented, and analytical approach with a proven ability to learn quickly. Proficiency in GCP, AWS and Linux Shell environments. Be a team player, customer focused with excellent interdisciplinary collaboration skills. ### Preferred Qualifications Practical experience utilizing GPU-accelerated C/C++ libraries or knowledge of GPUs and CUDA. Experience with CI/CD tools and concepts. Relocation benefits are not available for this posting. The expected salary range for this position based on the primary location of California is $145,300-$269,800. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below. ### Benefits Who we are A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact. Let’s build a healthier future, together. Roche is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants. ## At a glance - Posted by the employer: Not stated - First seen by OpenNash: Oct 11, 2026 - Last checked: Oct 18, 2026 - Listed for: 7 days - Location: Santa Clara - Employment type: Full-time - Pay: $145,300-$269,800[Apply on Roche Holding’s careers site →](https://roche.wd3.myworkdayjobs.com/roche-ext/job/Santa-Clara/Senior-Bioinformatics-Software-Engineer_202607-118174-2) ## More jobs at Roche Holding ### [Principal GPU Software Engineer](https://jobs.opennash.com/companies/roche-holding/jobs/ab83492dd3487433cfe5/) Santa Clara ### [Principal Software Development Engineer In Test](https://jobs.opennash.com/companies/roche-holding/jobs/74b816171ceeeeb6f7c6/) Santa Clara ### [Software Engineer](https://jobs.opennash.com/companies/roche-holding/jobs/fc3ca9daf52a0a64bdf5/) Santa Clara ### [Postdoctoral Fellow – Materials Engineering & Advanced Microfabrication - Next-Gen Sequencing and Diagnostics Systems, Research & Early Development](https://jobs.opennash.com/companies/roche-holding/jobs/fb05faa678be09fcdb18/) Santa Clara ### [Principal Scientist, Surface Chemistry](https://jobs.opennash.com/companies/roche-holding/jobs/72b0c087af91544d8588/) Santa Clara ## Similar jobs at other companies ### [Now Hiring: Intern - Bioinformatics in Geneva, Switzerland @ Labcorp](https://jobs.opennash.com/companies/labcorp-holdings/jobs/1979e3492e7a7da10715/) Labcorp Holdings · Geneva, Switzerland ### [Bioinformatics & AI Engineer](https://jobs.opennash.com/companies/amgen/jobs/12ec361661b5d7ad7877/) Amgen · India - Hyderabad ### [Bioinformatics Scientist/Engineer – DRAGEN Array](https://jobs.opennash.com/companies/illumina/jobs/cd042ca7a964240b6726/) Illumina ### [Bioinformatics Scientist](https://jobs.opennash.com/companies/amgen/jobs/48d30169e2e15e34a8c9/) Amgen · India - Hyderabad ### [Full Stack Software Engineer II and Senior Software Engineer- Microsoft Security - Multiple roles](https://jobs.opennash.com/companies/microsoft/jobs/ce8bde6800315a9405e1/) Microsoft · Israel, Multiple Locations OpenNash lists jobs from employers’ own careers sites and does not handle applications. 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