[Skip to main content](#main-content) [OpenNash Jobs](https://jobs.opennash.com/) [Hiring report](/reports/hiring/) · [All Revolution Medicines jobs](https://jobs.opennash.com/companies/revolution-medicines/) · [Search jobs](/search/) Revolution Medicines · Remote # Associate Director, Safety Operations, Japan Remote Remote Director Executive & Management Listed on Revolution Medicines’s official careers site. Posted October 5, 2026. Check that it is still open and apply there. [Apply on Revolution Medicines’s careers site →](https://www.revmed.com/careers-list/?gh_jid=8013758003) [OpenNash Jobs](https://jobs.opennash.com/) / [Revolution Medicines](https://jobs.opennash.com/companies/revolution-medicines/) / Associate Director, Safety Operations, Japan ## Job description Revolution Medicines is a global, commercial-state oncology company dedicated to discovering, developing and delivering innovative medicines for patients with RAS-addicted cancers. Leveraging its differentiated RAS(ON) tri-complex inhibitor platform, the company is advancing a broad, integrated portfolio of oral RAS(ON) inhibitors designed to directly target the active, cancer-driving state of RAS. Founded on rigorous scientific inquiry and a willingness to challenge long-held assumptions, Revolution Medicines is committed to changing the trajectory of disease for patients with RAS-addicted cancers worldwide. Our people are united by a shared way of working: follow the science, challenge assumptions, act with urgency and hold ourselves to a high standard of rigor—all in service of patients. ### The Opportunity The Associate Director, Safety Operations, Japan is responsible for providing safety related operational expertise to safety management in Japan. The individual will be responsible for ensuring the timely, accurate, and compliant processing and management of safety information collection and reporting in collaboration with Global Patient Safety Operation team and other internal stakeholders, CROs, and other external partners. ### Key Responsibilities ICSR and Safety Reporting Operations: Coordinate and review ICSR processing, follow-up, case quality review, expedited reporting, ensuring timely and compliant execution. ### Safety Data Quality and Reconciliation Review safety data quality and reconciliation activities, identify discrepancies or data quality issues, and coordinate appropriate follow-up and resolution. ### Aggregate Reporting Coordinate and review periodic and aggregate safety reports in Japan, ensuring completeness, consistency, quality, and compliance with applicable requirements. ### Safety Agreements and Information Exchange Coordinate the implementation and operational management of Safety Agreements and Pharmacovigilance Agreements (PVAs), including safety information exchange, agreed responsibilities, and reporting timelines. ### Japan Pharmacovigilance Operations Coordinate and review Japan-specific pharmacovigilance operations in accordance with applicable GVP/GPSP requirements and local procedures, including post-marketing safety activities such as EPPV and RMP-related risk minimization measures. ### Compliance, Audit and Inspection Readiness Coordinate self-inspections, internal audits, and regulatory inspections; identify and escalate operational and compliance issues; and follow up on CAPA implementation and issue resolution. ### Vendor Oversight Monitor and review the quality, completeness, accuracy, and timeliness of pharmacovigilance activities and deliverables performed by CROs and other external partners, and follow up on identified issues and corrective actions. ### Process and Procedure Management Develop and maintain Japan-specific pharmacovigilance procedures, work instructions, and operational workflows in alignment with applicable GVP/GPSP requirements, global processes, and local operational needs. ### Training and Competency Coordinate and support pharmacovigilance training for relevant employees and external partners, and maintain appropriate training records in accordance with applicable requirements. ### Required Skills, Experience and Education Bachelor’s degree in a healthcare field. Minimum of 7 years of relevant experience in pharmacovigilance/patient safety operational activities. Hands-on experience working with CROs/vendors and management of external resources. Strong background in safety reporting regulatory compliance and safety reporting/regulations both for clinical trials and post-marketing. Comprehensive knowledge of Japanese safety-related regulations (GVP/GPSP) is required. Ability to develop and maintain pharmacovigilance procedures, work instructions, and operational workflows in accordance with applicable requirements and global processes. Ability to identify operational and compliance issues, assess their impact, prioritize actions, and coordinate timely resolution. Strong collaboration and communication skills, with the ability to work effectively with internal stakeholders, global safety teams, CROs, and other external partners. Strong learning orientation, curiosity, and commitment to science and patients. Business-level English and native-level Japanese proficiency. Experience within a global and multicultural environment. ### Preferred Skills Master’s Degree or higher in a healthcare field. Experience establishing or improving pharmacovigilance processes, procedures, work instructions, and operational workflows in a developing organization. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com. #LI-RY1 #LI-Hybrid We are aware of recent recruitment scams in which individuals or organizations falsely represent themselves as being affiliated with Revolution Medicines. These scams may appear as false job advertisements or unsolicited contacts through communication or chat platforms, email, phone, or text message. Please note that Revolution Medicines does not extend unsolicited employment offers and will never ask candidates to provide financial information, purchase equipment, or pay fees as part of the hiring process. All legitimate communication from Revolution Medicines will come from an official @revmed.com email address. If you believe you’ve been contacted by someone impersonating a Revolution Medicines recruiter, please report it to careers@revmed.com so we can share these impersonations with our IT team for tracking and awareness. ## At a glance - Posted by the employer: Oct 5, 2026 - First seen by OpenNash: Oct 11, 2026 - Last checked: Oct 18, 2026 - Listed for: 13 days - Location: Remote - Work arrangement: Remote[Apply on Revolution Medicines’s careers site →](https://www.revmed.com/careers-list/?gh_jid=8013758003) ## More jobs at Revolution Medicines ### [Associate Director, FP&A, Japan](https://jobs.opennash.com/companies/revolution-medicines/jobs/ac0c633882f002c2bd60/) Remote ### [Associate Director, New Product Planning & Compound Strategy, Lung Cancer and Companion Diagnostics, Japan](https://jobs.opennash.com/companies/revolution-medicines/jobs/93540ea612c5c0cac82e/) Remote ### [Associate Director, Regional Insights and Engagement, Japan](https://jobs.opennash.com/companies/revolution-medicines/jobs/6d08fd83d8c68de75c93/) Remote ### [Associate Director, Safety Science, Japan](https://jobs.opennash.com/companies/revolution-medicines/jobs/d2f272f303b1c5667549/) Remote ### [Associate Director, Safety Systems, Japan](https://jobs.opennash.com/companies/revolution-medicines/jobs/a13a14de4eb064c47a66/) Remote ## Similar jobs at other companies ### [Senior Manager, Environmental Health and Safety - Japan](https://jobs.opennash.com/companies/sandisk/jobs/f89c8adc334ff0ec8310/) Sandisk ### [managing director japan](https://jobs.opennash.com/companies/richemont/jobs/eba50d0cd23c4e69accc/) Richemont ### [Senior Manager, Global Operations Finance – JV Finance (Japan Operations)](https://jobs.opennash.com/companies/sandisk/jobs/210ec71d6952f24ecb0c/) Sandisk ### [Compliance Director – Business Partnering & Advisory, Japan](https://jobs.opennash.com/companies/gsk/jobs/4b1664f134793dcac800/) GSK · Akasaka, Tokyo, Japan ### [[Innovative Medicine] Associate Director, PV Systems and Vendor Management, Local Medical Safety, Japan](https://jobs.opennash.com/companies/johnson-johnson/jobs/f20d784d636022437659/) Johnson & Johnson · Chiyoda, Tokyo, Japan OpenNash lists jobs from employers’ own careers sites and does not handle applications. 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