[Skip to main content](#main-content) [OpenNash Jobs](https://jobs.opennash.com/) [Hiring report](/reports/hiring/) · [All Novartis jobs](https://jobs.opennash.com/companies/novartis/) · [Search jobs](/search/) Novartis # Clinical Program Leader Cpl $248,500.00 - 461,500.00 Healthcare & Clinical Listed on Novartis’s official careers site. Listed as of October 18, 2026. Check that it is still open and apply there. [Apply on Novartis’s careers site →](https://www.novartis.com/careers/career-search/job/details/req-10077151-clinical-program-leader-cpl) [OpenNash Jobs](https://jobs.opennash.com/) / [Novartis](https://jobs.opennash.com/companies/novartis/) / Clinical Program Leader Cpl ## Job description ### Location Cambridge, MA. Hybrid May consider DWA, but candidates local to onsite preferred #LI-HybridExperience will determine which level 6 (Senior CPL or CPL) is appropriate after interview process based on skills and experience. ### CPL Provides strategic medical guidance and leads the development of experimental oncology agents in the TCO portfolio, beginning with PE / DC (Portfolio Entry / Drug Candidate) of preclinical development and continuing through TDP (Transition Decision Point).Major AccountabilitiesProvides strategic medical and scientific leadership and expertise to all line functions on the project team for the development of new oncology agents (e.g., small molecules, biologics, radioligand therapies) that are in preclinical development, typically beginning at the PE / DCCreates clinical development strategies for new oncology agents within the PE/ DC to TDP timeframe. The development strategy combines the CPL’s medical knowledge with the expertise of colleagues in a wide range of other disciplines (e.g., Clinical Pharmacology, Biostatistics) to optimize the clinical development strategy. Delivers solutions within functions, across functions, and on global projects, developing independent approach to TCO strategy. Although registration studies are not within the responsibility of TCO, the CPL must provide an early clinical development strategy that foresees and supports subsequent registration trials. Development of the Integrated Development Plan Approval (IDPA) in alignment with CPL Disease Area Leads (DALs), Development (DEV), Strategy & Growth (S&G), and Commercial teamsLead Biomedical Research Early Program Teams (BPTs) to enable the start of clinical development and continuing through clinical trials needed to support TDP. May lead multiple global project teamsIntegrates preclinical information (pharmacology, toxicology, and pharmacokinetics) and interprets implications for clinical development, as articulated in the Investigator’s Brochure and First-in-Human protocolCollaborates with clinical scientists to develop clinical protocols for TCO compounds and develop the instruments needed to implement, interpret and report them (e.g., case report forms, report and analysis plans, clinical study reports)Applies own medical knowledge to guide the safe, ethical and efficient conduct of the trials under own responsibility. Knowledgeable in Good Clinical Practice guidelines and Novartis Standard Operating Procedures and strives to maintain compliance with themLiaises with outside experts, investigators, and regulatory authorities in oncology, and represents own projects to those groups and authoritiesWrites and reviews abstracts/manuscripts etc. for presentation/publications at internal/external meetingsParticipates in task forces to support continuous improvement and other management objectives. Operational responsibility for quality and complianceMay provide informal mentorship to less experienced CPLsQualifications: Education:MD or DO degreeBoard-certification in an oncology specialty and PhD-level science are preferred Languages: Fluent English – Oral and writtenExperience/Professional requirement: At least 2 years of pharmaceutical/biotech industry experience in oncology clinical trials plus the equivalent duration experience from an academic medical center. If limited or no Pharmaceutical industry experience, then comparable senior academic experience in translational oncology and clinical researchRecognized as an expert in your field by external medical experts. External candidates have a substantial record of publication and international recognitionExcellent interpretation of oncology preclinical data (molecular biology, pharmacology, pharmacokinetics, and toxicology)Strong knowledge of the application of PK/PD and biostatistics to clinical development and clinical trialsProven ability to analyze and interpret efficacy and safety data relating to oncologyKnowledge of GCP and world-wide regulatory requirements for clinical trials and oncologyExcellent medical/scientific writing skillsSuccessful track record of strategic thinkingProven ability to develop and inspire project/line/matrix multidisciplinary teams in a global environmentExcellent personal ethical integrity and a commitment to improving the outcomes for patients with malignanciesExcellent written and oral English communication/presentation skillsStrong office IT skillsNovartis Compensation and Benefit Summary: The salary for this position is expected to range between $248,500.00 - 461,500.00 USD Annual per year.The final salary offered is determined based on factors like, but not limited to, relevant skills and experience, and upon joining Novartis will be reviewed periodically. Novartis may change the published salary range based on company and market factors.Your compensation will include a performance-based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards.US-based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a variety of other benefits. In addition, employees are eligible for a generous time off package including vacation, personal days,holidays and other leaves. ## At a glance - Posted by the employer: Not stated - First seen by OpenNash: Jul 17, 2026 - Last checked: Oct 18, 2026 - Listed for: 93 days - Pay: $248,500.00 - 461,500.00[Apply on Novartis’s careers site →](https://www.novartis.com/careers/career-search/job/details/req-10077151-clinical-program-leader-cpl) ## More jobs at Novartis ### [Japan Program Clinical Head Crm](https://jobs.opennash.com/companies/novartis/jobs/6e38ca74b11c1a09eaa5/) ### [Medical Information Agent](https://jobs.opennash.com/companies/novartis/jobs/cc16de5f6fa91e640f4b/) ### [Medical Advisor Immu Zh Cn](https://jobs.opennash.com/companies/novartis/jobs/4f8ad58a6f05f3a486dc/) ### [Medical Advisor Neuroscience Zh Cn](https://jobs.opennash.com/companies/novartis/jobs/28e76546c2c637c2e5a6/) ### [Senior Clinical Sciences Trial Leader](https://jobs.opennash.com/companies/novartis/jobs/8c95ad8446573d92b220/) ## Similar jobs at other companies ### [Director of Customer Experience & Integrated Quality Program Leader](https://jobs.opennash.com/companies/totalenergies/jobs/9883869be83675775b78/) TotalEnergies ### [Vehicle CAE - Project Leader NVH_Waiting Job Req](https://jobs.opennash.com/companies/renault/jobs/2116e451b59356a4e70d/) Renault ### [Program Lead Ii Clinical Program Development Director Level In Branchburg Nj Jid 33132](https://jobs.opennash.com/companies/abbvie/jobs/e6f6e2eaaaead172ed80/) AbbVie ### [Program Lead Ii Clinical Program Development Director Level In Irvine Ca Jid 33130](https://jobs.opennash.com/companies/abbvie/jobs/3d84c8e035c66d5fb40a/) AbbVie OpenNash lists jobs from employers’ own careers sites and does not handle applications. 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