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Neurocrine Biosciences · US CA San Diego

# Senior Medical Director, Clinical Development, Obesity

US CA San Diego Director $301,100.00-$411,000.00 Healthcare & Clinical 

Listed on Neurocrine Biosciences’s official careers site. Listed as of October 18, 2026. Check that it is still open and apply there.
[Apply on Neurocrine Biosciences’s careers site →](https://neurocrine.wd5.myworkdayjobs.com/Neurocrinecareers/job/US-CA-San-Diego/Senior-Medical-Director--Clinical-Development--Obesity_R7051)

[OpenNash Jobs](https://jobs.opennash.com/) / [Neurocrine Biosciences](https://jobs.opennash.com/companies/neurocrine-bioscience/) / Senior Medical Director, Clinical Development, Obesity

## Job description

### Who We Are

Neurocrine Biosciences is a leading biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs. We are dedicated to discovering, developing and commercializing life-changing treatments for patients with under-addressed neurological, psychiatric, endocrine and immunological disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington's disease, classic congenital adrenal hyperplasia, hyperphagia in Prader-Willi syndrome, endometriosis* and uterine fibroids*, as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas.

For more than three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders, because you deserve brave science. For more information, visit neurocrine.com, and follow the company on LinkedIn, X, Facebook and YouTube. ( *in collaboration with AbbVie) At Neurocrine, strong leadership drives both business results and team success.

We look for leaders who think strategically, anticipate what’s ahead and set clear direction, while building and empowering high-performing teams. Successful leaders foster an environment where people are motivated to do their best work and deliver meaningful, measurable impact through sound decision-making and accountability.

### About the Role

The Senior Medical Director, Clinical Development will serve as a key medical and scientific leader responsible for defining and executing clinical development strategies for Neurocrine’s obesity pipeline. This role provides independent medical leadership across Phase 1–3 clinical programs and partners closely with cross-functional teams including Clinical Operations, Clinical Project Management, Biometrics, Regulatory Affairs, Drug Safety, Translational Medicine, and Preclinical/Clinical Pharmacology.

As the Program/Therapeutic Medical Lead, the Senior Medical Director is accountable for the creation and execution of clinical development plans that support regulatory approval and advance Neurocrine’s development portfolio.

This role provides expert medical and strategic guidance to navigate complex scientific, clinical, and regulatory challenges, ensuring high-quality, compliant, and efficient development of novel therapies. _ Your Contributions (include, but are not limited to): Clinical Development Strategy & Leadership
- Develops and leads clinical development strategies for assigned obesity programs, with accountability for study design and medical integrity of clinical trials across Phase 1–3
- Serves as the Program/Therapeutic Medical
- Lead on cross-functional Program Teams, providing medical leadership and clinical input into integrated development plans
- Drives execution of the clinical development plan, ensuring alignment with corporate objectives, regulatory strategy, and scientific rationale
- Translates clinical strategy into actionable study designs and operational plans that deliver high-quality data and meaningful outcomes Study Design, Execution & Oversight
- Leads preparation of clinical study synopses and is a major contributor to protocols, major amendments, and clinical study reports
- Oversees the design of data collection strategies and ensures appropriate interpretation and integration of clinical data
- Partners with Clinical Operations to oversee clinical trial execution in accordance with NBI SOPs, Good Clinical Practice (GCP), and applicable regulatory requirements
- Conducts medical assessment and disposition of adverse events in collaboration with Drug Safety, and provides ongoing evaluation of benefit–risk throughout clinical development

### Cross-Functional & External Engagement
- Collaborates closely with internal stakeholders to support study activities requiring medical expertise
- Engages external experts, investigators, and key opinion leaders to inform strategy, optimize trial design, and advance programs
- Assists in identification and selection of clinical investigators and serves as Sponsor medical monitor/representative
- Works with Medical Affairs and external partners to communicate clinical data and establish new collaborations

### Data Interpretation & Scientific Communication
- Leads analysis, interpretation, and presentation of clinical study results to internal and external audiences
- Provides strategic direction for scientific disclosures, including conference abstracts, presentations, and peer-reviewed publications
- Partners with Research and Translational Medicine to define biomarker strategies that enhance early clinical evaluation and decision-making Portfolio & Organizational Leadership Interfaces with Research, Product Development, and Business Development to assess new product opportunities and shape clinical research strategies
- Identifies resource needs and contributes to budget planning, personnel forecasting, and development of clinical teams Plays a key role in recruiting, mentoring, and developing clinical staff, and in identifying and managing external consultants and CROs
- Contributes to the development and implementation of clinical development policies, processes, and best practices Requirements: Education & Training MD or DO (or equivalent) degree in relevant clinical specialty for the therapeutic area required AND 4+ years clinical experience with broad bio/pharmaceutical/CRO industry experience in drug development OR Accredited residency training and board certification preferred AND Experience & Expertise Recognized internal thought leader with deep expertise in clinical development Comprehensive understanding of the drug development process, including regulatory, technical, and business considerations
- Proven track record providing clinical leadership for INDs, NDAs, or other regulatory submissions and interactions with global regulatory agencies
- Strong knowledge of GCP, regulatory procedures, translational medicine, biomarker development, study design, biostatistics, and data interpretation
- Demonstrated success leading cross-functional, matrixed teams and managing external CROs and vendors, particularly in small or agile organizations Experience driving program strategy from early development through late-stage execution Leadership & Core Competencies Strategic thinker with the ability to translate vision into executable plans and deliver results
- Strong mentoring and people leadership skills, with experience leading direct and indirect teams Highly collaborative with exceptional interpersonal skills and the ability to influence across functions and externally Outstanding oral and written communication skills, with the ability to clearly convey complex scientific concepts to diverse audiences Flexible, adaptable, and self-motivated, with the ability to manage multiple priorities in a fast-paced environment
- Demonstrated project management capability and attention to detail
- Proficiency with standard business and clinical documentation tools (word processing, spreadsheets, presentations, databases, and archiving systems) #LI-KM1 Neurocrine Biosciences is an EEO/Disability/Vets employer.

We are committed to building a workplace of belonging, respect, and empowerment, and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don’t line up to exactly what we have outlined in the job description. _ The annual base salary we reasonably expect to pay is $301,100.00-$411,000.00.

Individual pay decisions depend on various factors, such as primary work location, complexity and responsibility of role, job duties/requirements, and relevant experience and skills. In addition, this position offers an annual bonus with a target of 35% of the earned base salary and eligibility to participate in our equity based long term incentive program. Benefits offered include a retirement savings plan (with company match), paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans.

## At a glance
- Posted by the employer: Not stated
- First seen by OpenNash: Oct 11, 2026
- Last checked: Oct 18, 2026
- Listed for: 7 days
- Location: US CA San Diego
- Pay: $301,100.00-$411,000.00[Apply on Neurocrine Biosciences’s careers site →](https://neurocrine.wd5.myworkdayjobs.com/Neurocrinecareers/job/US-CA-San-Diego/Senior-Medical-Director--Clinical-Development--Obesity_R7051)

## More jobs at Neurocrine Biosciences

### [Associate Clinical Trials Director](https://jobs.opennash.com/companies/neurocrine-bioscience/jobs/f067f9430e1abd7c63a9/)

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### [Associate Director, Clinical Supply Chain](https://jobs.opennash.com/companies/neurocrine-bioscience/jobs/4cadc20b1873e38a6c98/)

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### [Director, Clinical Operations](https://jobs.opennash.com/companies/neurocrine-bioscience/jobs/181ec576473d16fc47d2/)

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### [Global Head, Medical Drug Safety & Pharmacovigilance](https://jobs.opennash.com/companies/neurocrine-bioscience/jobs/378ec840ae3d1ebf1e37/)

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### [Medical Affairs Director](https://jobs.opennash.com/companies/neurocrine-bioscience/jobs/9c355405751c0a32b522/)

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