[Skip to main content](#main-content) [OpenNash Jobs](https://jobs.opennash.com/) [Hiring report](/reports/hiring/) · [All Merck KGaA, Darmstadt, Germany and its affiliates jobs](https://jobs.opennash.com/companies/merck-kgaa-germany/) · [Search jobs](/search/) Merck KGaA, Darmstadt, Germany and its affiliates · St Louis, MO # GMP Manufacturing Support Supervisor-Day Shift St. Louis, Missouri, United States Full-time Manager or lead $85,700.00 - $149,400.00 Manufacturing & Production Listed on Merck KGaA, Darmstadt, Germany and its affiliates’s official careers site. Posted September 15, 2026. Check that it is still open and apply there. [Apply on Merck KGaA, Darmstadt, Germany and its affiliates’s careers site →](https://careers.merckgroup.com/global/en/job/MQAMKDGLOBAL302804EXTERNALENGLOBAL/GMP-Manufacturing-Support-Supervisor-Day-Shift) [OpenNash Jobs](https://jobs.opennash.com/) / [Merck KGaA, Darmstadt, Germany and its affiliates](https://jobs.opennash.com/companies/merck-kgaa-germany/) / GMP Manufacturing Support Supervisor-Day Shift ## Job description Work Your Magic with us! Start your next chapter and join MilliporeSigma. Ready to explore, break barriers, and discover more? We know you’ve got big plans – so do we! Our colleagues across the globe love innovating with science and technology to enrich people’s lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us. This role does not offer sponsorship for work authorization. External applicants must be eligible to work in the US. ### Your Role At MilliporeSigma, the GMP Manufacturing Support Supervisor -Day Shift at our Cherokee site/3300 S. Second Ave, St Louis, will play a key role within our GMP Operations Systems & Support team. This team supports Manufacturing through various functions including buffer manufacturing, training, compliance, equipment and facility cleaning, and raw material coordination. Expectations of the GMP Operations System & Support team are to ensure compliance and readiness within our GMP Manufacturing teams, ultimately enabling high manufacturing success. Job duties include: Shift Details: This role will support 24/7 manufacturing operations and work 12-hour shifts from 6:00am – 6:30pm including a 5% shift differential Lead production scientists and operators in the scale-up, technology transfer, and execution of cGMP buffer manufacturing. Lead Facility Operators in supporting Manufacturing through maintaining cleanliness of manufacturing facilities and equipment, staging of equipment and supplies, waste disposal, and other various manufacturing support activities. Develop employees’ knowledge and skills to improve performance and expand abilities as well as to coordinate the group’s efforts to assist meeting the departmental, company, and customer’s objectives. Oversee the manufacturing of processing aids and excipients, regulated by the Food and Drug Administration and other regulatory bodies. Adhere to protocols consistent with, and established according to, current Good Manufacturing Practices. Work cross-functionally with Project Management, Technical Operations, Process & Analytical Development, Quality Control, Quality Assurance, Packaging, Materials Management, Engineering, and Maintenance. Interact with our customers’ project management, technical and quality teams. Maintain departmental goals and objectives in a safe manner and in compliance with all applicable federal, state, and company regulations (OSHA, EPA, FDA, EMA etc.). Responsible for the management of capital for equipment and facility improvements, including balancing the departmental budget. Support department efforts toward Process Improvement and company goals. Revise and approve procedures, batch records, and other documentation to ensure compliance with cGMP guidelines. Ensure employees remain current with all department and site training requirements. Lead root cause investigations and implement effective corrective and preventative actions related to manufacturing deviations. Provide leadership and support of safety initiatives within production operations to ensure compliance to OSHA requirements. Ensure tasks are done in accordance with approved site procedures, batch records and protocols. ### Physical Attributes Stand for extended periods of time Lift, push, and or pull up to 35lbs. Wear mask, safety shoes, gloves, Tyvek suits, respirator, and related personal protective equipment ### Who You Are - Minimum Qualification: Bachelor’s Degree Chemistry, Biology Biochemistry or other Life Science field OR in Chemical Engineering, Mechanical Engineering or other Engineering fields - 2+ years of life science manufacturing experience in a cGMP setting - 1+ year of Management, Supervisory, or Lead experience OR High School Diploma or GED 6+ years of life science manufacturing experience in a cGMP setting - 1+ year of Management, Supervisory, or Lead experience Preferred Qualifications: 3 + years of Management, Supervisory or Lead experience in GxP environment Customer interfacing audit experience - Knowledge of Six Sigma concepts/Lean Manufacturing or process improvement - Familiarity with buffer manufacturing, facility and equipment cleaning, and raw material management Strong Microsoft Office experience for Manufacturing/Operating procedure writing, technical report generation, product tracking and trending data analysis and Operational Excellence reports - Strong interpersonal skills, conflict resolution experience, written, and verbal communication skills RSREMD Pay Range for this position: $85,700.00 - $149,400.00 The offer range represents the anticipated low and high end of the base pay compensation for this position. The actual compensation offered will be determined by factors such as location, level of experience, education, skills, and other job-related factors. Position may be eligible for sales or performance-based bonuses. Benefits offered by the Company include health insurance, paid time off (PTO), retirement contributions, and other perquisites. For more information click here. ### What we offer We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We believe that this variety drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress! Apply now and become a part of a team that is dedicated to Sparking Discovery and Elevating Humanity! ## At a glance - Posted by the employer: Sep 15, 2026 - First seen by OpenNash: Oct 19, 2026 - Last checked: Oct 19, 2026 - Listed for: 34 days - Location: St. Louis, Missouri, United States - Employment type: Full-time - Pay: $85,700.00 - $149,400.00[Apply on Merck KGaA, Darmstadt, Germany and its affiliates’s careers site →](https://careers.merckgroup.com/global/en/job/MQAMKDGLOBAL302804EXTERNALENGLOBAL/GMP-Manufacturing-Support-Supervisor-Day-Shift) ## More jobs at Merck KGaA, Darmstadt, Germany and its affiliates ### [GMP Technical Writer](https://jobs.opennash.com/companies/merck-kgaa-germany/jobs/1dfd12cc822eae1e85d1/) St. Louis, Missouri, United States ### [Quality Assurance Training Specialist II](https://jobs.opennash.com/companies/merck-kgaa-germany/jobs/97b0436ff4b2efee33ff/) St. Louis, Missouri, United States ### [Site Head Cherokee, St Louis](https://jobs.opennash.com/companies/merck-kgaa-germany/jobs/71bcedb6dce94c7e400d/) St. Louis, Missouri, United States ### [Associate Architects](https://jobs.opennash.com/companies/merck-kgaa-germany/jobs/69bb5ac1894151e0a138/) St. Louis, Missouri, United States ### [Associate Production Scientist-Trainer](https://jobs.opennash.com/companies/merck-kgaa-germany/jobs/9291591e223ccc64e2d3/) St. Louis, Missouri, United States ## Similar jobs at other companies ### [Manufacturing Supervisor](https://jobs.opennash.com/companies/steris/jobs/ab1133276e1cc927a22f/) Steris · St. Louis, Missouri, United States ### [Supervisor, GMP Lab - Biopharmaceuticals](https://jobs.opennash.com/companies/thermo-fisher-scientific/jobs/721ce59b07c88f0028c5/) Thermo Fisher Scientific · Middleton, Wisconsin, United States of America ### [Manufacturing Support](https://jobs.opennash.com/companies/fastenal/jobs/adf1e7cfac2874a8a5af/) Fastenal · Wallingford, CT ### [Manufacturing Supervisor](https://jobs.opennash.com/companies/lockheed-martin/jobs/099a6e68782a4bb54ad4/) Lockheed Martin · Archbald, PA OpenNash lists jobs from employers’ own careers sites and does not handle applications. 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