[Skip to main content](#main-content) [OpenNash Jobs](https://jobs.opennash.com/) [Hiring report](/reports/hiring/) · [All Merck KGaA, Darmstadt, Germany and its affiliates jobs](https://jobs.opennash.com/companies/merck-kgaa-germany/) · [Search jobs](/search/) Merck KGaA, Darmstadt, Germany and its affiliates · Lenexa, KS # Principal Project Engineer Lenexa, Kansas, United States Full-time Senior individual contributor $106,500 - $172,900 Operations Listed on Merck KGaA, Darmstadt, Germany and its affiliates’s official careers site. Posted September 6, 2026. Check that it is still open and apply there. [Apply on Merck KGaA, Darmstadt, Germany and its affiliates’s careers site →](https://careers.merckgroup.com/global/en/job/MQAMKDGLOBAL302123EXTERNALENGLOBAL/Principal-Project-Engineer) [OpenNash Jobs](https://jobs.opennash.com/) / [Merck KGaA, Darmstadt, Germany and its affiliates](https://jobs.opennash.com/companies/merck-kgaa-germany/) / Principal Project Engineer ## Job description Work Your Magic with us! Start your next chapter and join MilliporeSigma. Ready to explore, break barriers, and discover more? We know you’ve got big plans – so do we! Our colleagues across the globe love innovating with science and technology to enrich people’s lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us. This role does not offer sponsorship for work authorization. External applicants must be eligible to work in the US. ### Your Role As a Principal Project Engineer at the Lenexa, KS site, you will lead key projects related to the design, qualification, and optimization of the cell culture media manufacturing equipment and facilities to ensure safe, compliant, and scalable production of high-quality media for biopharmaceutical applications. This includes technical project management for both capital projects and process improvements. You will develop project scope and ensure seamless implementation of the most efficient, viable technical solution in alignment with internal standards. You will collaborate with process engineering, manufacturing, quality, EHS, and maintenance to ensure robust design, commissioning, qualification, and operational readiness. Additionally, you will drive project timing, budget, and risk management, and prepare and present status reports to leadership and stakeholders. You will ensure adherence to data integrity and change-control practices, owning the engineering change process, and you will mentor engineers and cross-functional teams to foster a culture of safety, quality, and continuous improvement. You will identify and implement cost-saving opportunities, technology upgrades, and energy/water efficiency improvements, and ensure facilities and equipment meet regulatory and MilliporeSigma corporate standards for cell culture media manufacturing operations. ### Who You Are Minimum Qualifications: Education: Bachelor’s degree in Chemical, Biochemical, Mechanical, or Biomedical Engineering (or a closely related field); Master’s degree preferred 5+ years of professional engineering experience Experience managing projects over $1M Preferred Qualifications: Technical competencies: Experience with validation strategies (IQ/OQ/PQ) and commissioning/ qualification activities; familiarity with automation concepts, sensors, control systems, data integrity, and change control. ### Skills Proven project management and leadership capabilities; ability to influence across functions; excellent problem-solving, risk assessment, and decision-making skills; strong communication and technical writing abilities Experience in medical, biotechnology, or Bio-pharmaceutical manufacturing environment is highly preferred PMP certification preferred Pay Range for this position: $106,500 - $172,900 The offer range represents the anticipated low and high end of the base pay compensation for this position. The actual compensation offered will be determined by factors such as location, level of experience, education, skills, and other job-related factors. Position may be eligible for sales or performance-based bonuses. Benefits offered by the Company include health insurance, paid time off (PTO), retirement contributions, and other perquisites. For more information click here. ### What we offer We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We believe that this variety drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress! Apply now and become a part of a team that is dedicated to Sparking Discovery and Elevating Humanity! ## At a glance - Posted by the employer: Sep 6, 2026 - First seen by OpenNash: Oct 19, 2026 - Last checked: Oct 19, 2026 - Listed for: 43 days - Location: Lenexa, Kansas, United States - Employment type: Full-time - Pay: $106,500 - $172,900[Apply on Merck KGaA, Darmstadt, Germany and its affiliates’s careers site →](https://careers.merckgroup.com/global/en/job/MQAMKDGLOBAL302123EXTERNALENGLOBAL/Principal-Project-Engineer) ## More jobs at Merck KGaA, Darmstadt, Germany and its affiliates ### [Manufacturing Supervisor](https://jobs.opennash.com/companies/merck-kgaa-germany/jobs/a14e6093a54f82abc0d1/) Lenexa, Kansas, United States ### [Advanced Packaging Principle Integration Technologist (Principal Engineer, 10 years+ experience)](https://jobs.opennash.com/companies/merck-kgaa-germany/jobs/6c7a051f85398fd2e61e/) Hsinchu, Hsinchu County, Taiwan ### [Advanced Packaging Principle Integration Technologist (Principal Engineer, 10 years+ experience)](https://jobs.opennash.com/companies/merck-kgaa-germany/jobs/b78fadfe589c7fc6d79e/) Seoul, Korea ### [Agentic AI Platform Engineer](https://jobs.opennash.com/companies/merck-kgaa-germany/jobs/c74e3fcd7e32856cc56b/) Bangalore, Karnataka, India ### [Agentic AI Platform Engineer](https://jobs.opennash.com/companies/merck-kgaa-germany/jobs/7feccb495e2090ce4e87/) Mollet del Valles, Barcelona, Spain ## Similar jobs at other companies ### [Senior Principal Systems - Agile Project Engineer (Hybrid & Relocation Available)](https://jobs.opennash.com/companies/bae-systems/jobs/6e282311d6b1f0d76c32/) BAE Systems · Cedar Rapids, Iowa, United States ### [Principal Chipset Project Engineer – Hardware PCB/Platform Systems for Personal Compute (PC)](https://jobs.opennash.com/companies/qualcomm/jobs/8496750fa2d531d5b368/) Qualcomm · San Diego, California, United States of America ### [Consulting Project Principal Consultant](https://jobs.opennash.com/companies/oracle/jobs/e2298e357b1388d59773/) Oracle · United States ### [Senior Principal Project Engineering Manager - Factory Transition (Hybrid and Relocation Available)](https://jobs.opennash.com/companies/bae-systems/jobs/e9b4660ed19a47c08bcb/) BAE Systems · Cedar Rapids, Iowa, United States ### [Principal Project Management/ Sr. Principal Project Management](https://jobs.opennash.com/companies/northrop-grumman/jobs/fa315d0686a909f96eb5/) Northrop Grumman · United States-California-Sunnyvale OpenNash lists jobs from employers’ own careers sites and does not handle applications. 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