[Skip to main content](#main-content) [ OpenNash ](https://opennash.com/) / [Jobs](https://jobs.opennash.com/) [ 01 Search jobs](https://jobs.opennash.com/search/)[ 02 Companies](https://jobs.opennash.com/explore/)[ 03 Hiring report](https://jobs.opennash.com/reports/hiring/)[ 04 AI assistants](https://jobs.opennash.com/connect/)[ 05 How it works](https://jobs.opennash.com/methodology/) Merck & Co. · BRA - Sao Paulo - Sao Paulo # Clinical Research Manager BRA - Sao Paulo - Sao Paulo Full-time Manager or lead Healthcare & Clinical Listed on Merck & Co.’s official careers site. Posted November 7, 2026. Check that it is still open and apply there. [Apply on Merck & Co.’s careers site →](https://msd.wd5.myworkdayjobs.com/SearchJobs/job/BRA---Sao-Paulo---Sao-Paulo-Torre-Z/Clinical-Research-Manager_R425431) [OpenNash Jobs](https://jobs.opennash.com/) / [Merck & Co.](https://jobs.opennash.com/companies/merck-co/) / Clinical Research Manager ## Job description ### Job Description Our Global Clinical Trial team is at the heart of advancing our clinical development portfolio, turning science into meaningful outcomes for patients. We are looking for a Clinical Research Manager (CRM) to drive the end-to-end execution of clinical studies in Brazil. This role is primarily accountable for the end to end performance and project management for assigned protocols in a country in compliance with ICH/GCP and country regulations, our company policies and procedures, quality standards and adverse event reporting requirements internally and externally. Responsibilities include, but are not limited to: Main Point of Contact (POC) for assigned protocols and link between Country Operations and clinical trial team (CTT). ### Responsible for project management of the assigned studies pro-actively plans, drives and tracks execution and performance of deliverables/timelines/results to meet country commitments from feasibility and site selection, recruitment, execution and close out. Accountable for performance for assigned protocols in a country in compliance with ICH/GCP and country regulations, Our Company policies and procedures, quality standards and adverse event reporting requirements internally and externally. Reviews Monitoring Visits Reports and escalates performance issues and training needs to CRA manager and/or functional vendor and internal management as needed. - Performs Quality control visits as required - Leads local study teams to high performance: trains in the protocol other local roles, closely collaborates with and supports CRAs as protocol expert and coordinates activities across the different local country roles ensuring a strong collaboration Responsible for creating and executing a local risk management plan for assigned studies - Ensures compliance with CTMS, eTMF and other key systems in assigned studies - Escalates as needed different challenges and issues to TA Head/CRD/CQM and or CTT (as appropriate) Responsible for collaboration with functional outsourcing vendors, investigators, other external partners in assigned studies: Country POC for programmatically outsourced trials for assigned protocols. Collaborates internally with HQ functions and locally with PV, Regulatory and GMA to align on key decisions in his/her studies. GHH to be consulted as needed. As a customer-facing role, this position will build business relationships and represent Our Company with investigators Shares protocol-specific information and best practices across countries\clusters ### Required Experience Proven hands-on experience in end-to-end management of sponsor-led Phase I–III clinical trials, beyond site monitoring activities. Experience managing large-scale and/or highly complex clinical trials, including megatrials. Experience with complex study designs and operational models, with greater emphasis on study type, scale and complexity than on a specific therapeutic area. Strong knowledge of ICH-GCP, clinical research regulations and quality standards. Strong project management, risk management and cross-functional stakeholder management capabilities Required: Bachelor degree in Science (or comparable) ### English Proficiency Preferred Advanced degree, (e.g., Master degree, MD, PhD) "Temos orgulho de ser uma empresa que acredita no valor de trazer pessoas de diferentes perfis, talentosas e comprometidas. A maneira mais rápida de revolucionar a inovação é quando ideias diversas se reúnem em um ambiente inclusivo. Incentivamos nossos colaboradores a abordar os problemas coletivamente e desafiar de forma respeitosa o raciocínio uns dos outros. Somos um empregador focado em promover iguais oportunidades aos nossos colaboradores, comprometido a incentivar um local de trabalho inclusivo e diversificado." ### Additional location(s) Compensation Information Required Skills: Clinical Data Management, Clinical Research, Clinical Site Management, Clinical Trial Management, Good Clinical Practice (GCP), Risk Based Monitoring, Strategic Planning, Strategic Thinking, Vendor Management Preferred Skills: Current Employees apply HERE Current Contingent Workers apply HERE Search Firm Representatives Please Read Carefully Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails. ### Employee Status Regular Relocation: VISA Sponsorship: Travel Requirements: Flexible Work Arrangements: Hybrid Shift: Valid Driving License: Hazardous Material(s): Job Posting End Date: 11/18/2026 *A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date. ## At a glance - Posted by the employer: Nov 7, 2026 - First seen by OpenNash: Nov 8, 2026 - Last checked: Nov 8, 2026 - Listed for: 1 day - Location: BRA - Sao Paulo - Sao Paulo - Employment type: Full-time[Apply on Merck & Co.’s careers site →](https://msd.wd5.myworkdayjobs.com/SearchJobs/job/BRA---Sao-Paulo---Sao-Paulo-Torre-Z/Clinical-Research-Manager_R425431) ## Hiring at Merck & Co. - Open jobs: 837 - New in the last 7 days: After two weekly collections - Tracked since: Jul 10, 2026 [All Merck & Co. jobs](https://jobs.opennash.com/companies/merck-co/) · [Weekly hiring report](/reports/hiring/) ## More jobs at Merck & Co. ### [Clinical Research Associate I (CRA I) - São Paulo/SP](https://jobs.opennash.com/companies/merck-co/jobs/7b721b616a79ccec8a27/) BRA - Sao Paulo - Sao Paulo ### [Analista Fiscal Tributário - São Paulo](https://jobs.opennash.com/companies/merck-co/jobs/294636c159ceea92c61c/) BRA - Sao Paulo - Sao Paulo ### [Business Insights and Analytics Partner](https://jobs.opennash.com/companies/merck-co/jobs/fd827ef37690630af316/) BRA - Sao Paulo - Sao Paulo ### [Gerente Regional de Vendas (SC/PR) BU Ruminantes](https://jobs.opennash.com/companies/merck-co/jobs/b6eb434f4ad523e31336/) BRA - Sao Paulo - Sao Paulo ## Similar jobs at other companies ### [FSP Clinical Research Associate I/ Clinical Research Associate II](https://jobs.opennash.com/companies/thermo-fisher-scientific/jobs/06881e6c995965b186b5/) Thermo Fisher Scientific · Remote, Israel ### [Clinical Research Coordinator](https://jobs.opennash.com/companies/ge-healthcare-technologies/jobs/31afee860fb17ad00233/) GE HealthCare Technologies · Horten, Norway ### [Manager - Clinical Research Lead](https://jobs.opennash.com/companies/eli-lilly/jobs/9812cfd5593e66b53d8e/) Eli Lilly · Taipei City, Taiwan ### [Clinical Research Scientist – MR](https://jobs.opennash.com/companies/ge-healthcare-technologies/jobs/6697555f98a09bd7e575/) GE HealthCare Technologies · Seoul, Korea, Republic of OpenNash lists jobs from employers’ own careers sites and does not handle applications. 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