[Skip to main content](#main-content) [OpenNash Jobs](https://jobs.opennash.com/) [Hiring report](/reports/hiring/) · [All Merck & Co. jobs](https://jobs.opennash.com/companies/merck-co/) · [Search jobs](/search/) Merck & Co. · JPN - Tokyo - Chiyoda # R&D Clinical PK & Pharmacometrics Sr. Scientist JPN - Tokyo - Chiyoda Full-time Senior individual contributor Healthcare & Clinical Listed on Merck & Co.’s official careers site. Listed as of October 18, 2026. Check that it is still open and apply there. [Apply on Merck & Co.’s careers site →](https://msd.wd5.myworkdayjobs.com/SearchJobs/job/JPN---Tokyo---Chiyoda/R-D-Clinical-PK---Pharmacometrics-Sr-Scientist_R402185) [OpenNash Jobs](https://jobs.opennash.com/) / [Merck & Co.](https://jobs.opennash.com/companies/merck-co/) / R&D Clinical PK & Pharmacometrics Sr. Scientist ## Job description Job Description ・医薬品開発戦略に対して、臨床薬理/ファーマコメトリクスを活用した提案を行い、早期承認に貢献する ・他チームや臨床現場に対して、治験薬の臨床薬理学的情報を的確に提供するとともに、問題解決を行う ・プロトコールの試験デザイン・被験者数・解析方法並びに試料のサンプリングポイントなどを検討し、適切な提案を行う ・薬物動態（PK）解析を実施し、治験総括報告書の該当するセクションを作成する ・PK結果の速報を作成し配信する。 ・臨床現場に提供すべき治験薬の臨床薬理/薬物動態学的情報を精査し、非臨床ADMEを含む申請資料の臨床薬理関連部分に過不足無く盛り込む ・臨床現場に提供すべき治験薬の臨床薬理/薬物動態学的情報や用法・用量に関連する臨床薬理領域の電子データを特定し、戦略に応じて、適切に提出する ・PMDA相談の資料作成・当日の議論に臨床薬理担当者として加わり、承認に貢献する ・本社の担当者と継続的に連絡を取りながらこれらの業務を進める。 ・必要に応じてモデリング＆シミュレーション（M＆S）を実施する ・グループ内のM&Sスキル向上への提言及び下位部員に対するメンターとして教育・指導的役割を担う 応募条件 【必須（MUST）】 ・臨床薬理部門もしくは関連部門での3年～10年程度の実務経験 ・M＆S（population PK, PK－PDまたはExposure－Response解析）の知識・理解 ・非臨床ADMEの知識・理解 ・ノンコンパートメントPK解析の知識・理解 【歓迎（WANT）】 ・ノンコンパートメントPK解析の実務経験 ・M＆S（population PK, PK－PDまたはExposure－Response解析）の実務経験 ・各品目のプロジェクトチーム内で、他のメンバーと積極的に関わって議論/プレゼンできる方 ・海外の担当者とのメール、電話等でのコミュニケーションが可能で、関係を構築できる方 ・CDISC / non－CDISCの電子データ申請に関する基礎知識・経験があれば尚可 ・博士号（PhD）であれば尚可 Required Skills: Clinical Trial Planning, Data Analysis, English Communications, Japanese Language, Modeling Simulations, New Technology Integration, Oncology, Pharmacodynamics, Pharmacokinetics, Pharmacometrics, Pharmacotherapeutics, Regulatory Submissions, Scientific Publications, Teamwork Communication, Therapeutic Knowledge Preferred Skills: Current Employees apply HERE Current Contingent Workers apply HERE Search Firm Representatives Please Read Carefully Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails. ### Employee Status Regular Relocation: VISA Sponsorship: Travel Requirements: Flexible Work Arrangements: Hybrid Shift: Valid Driving License: Hazardous Material(s): Job Posting End Date: 12/31/2026 *A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date. ## At a glance - Posted by the employer: Not stated - First seen by OpenNash: Jul 10, 2026 - Last checked: Oct 18, 2026 - Listed for: 100 days - Location: JPN - Tokyo - Chiyoda - Employment type: Full-time[Apply on Merck & Co.’s careers site →](https://msd.wd5.myworkdayjobs.com/SearchJobs/job/JPN---Tokyo---Chiyoda/R-D-Clinical-PK---Pharmacometrics-Sr-Scientist_R402185) ## More jobs at Merck & Co. ### [Medical Affairs ID/Vaccine Executive Director](https://jobs.opennash.com/companies/merck-co/jobs/7fed4170ea8b105d51f0/) JPN - Tokyo - Chiyoda ### [Medical Affairs MSL (Infectious Diseases & Vaccines) (ワクチン領域)](https://jobs.opennash.com/companies/merck-co/jobs/6bb230b70665f0fa1199/) JPN - Tokyo - Chiyoda ### [Medical Affairs Oncology Medical Advisor (M.D.)](https://jobs.opennash.com/companies/merck-co/jobs/fbf61fad900af220a39f/) JPN - Tokyo - Chiyoda ### [Medical Affairs Oncology Scientific Content & Medical Information, Specialist](https://jobs.opennash.com/companies/merck-co/jobs/cdf086a185782d9656cd/) JPN - Tokyo - Chiyoda ### [Medical Affairs, Medical Advisor (Influenza)](https://jobs.opennash.com/companies/merck-co/jobs/6813175accc26369151c/) JPN - Tokyo - Chiyoda ## Similar jobs at other companies ### [Principal Scientist, Clinical Pharmacology & Pharmacometrics](https://jobs.opennash.com/companies/johnson-johnson/jobs/7b8c8a502df7b7f370c9/) Johnson & Johnson ### [Decision Scientist - Clinical Informatics (Clinical Data Standards)](https://jobs.opennash.com/companies/cvs-health/jobs/3549d29c96077c5c187a/) CVS Health ### [Clinical Scientist](https://jobs.opennash.com/companies/thermo-fisher-scientific/jobs/4d4d9107b85a316184b6/) Thermo Fisher Scientific · Shanghai, China ### [Clinical Scientist IRM - Lyon (h/f/nb)](https://jobs.opennash.com/companies/siemens/jobs/0b308c6e1c9b087f281d/) Siemens ### [Senior Statistical Programmer in Pharmacometrics (PM) support (Clinical Trials)](https://jobs.opennash.com/companies/iqvia/jobs/a20c013a96e51e856dd0/) IQVIA OpenNash lists jobs from employers’ own careers sites and does not handle applications. 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