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Jiangsu Hengrui Medicine · 中国 · 上海市

# 药化助理总监/副总监

中国 · 上海市 

Listed on Jiangsu Hengrui Medicine’s official careers site. Posted September 17, 2026. Check that it is still open and apply there.
[Apply on Jiangsu Hengrui Medicine’s careers site →](https://app.mokahr.com/social-recruitment/hengrui/145996#/job/cfc2809b-445f-4b62-933c-c4ff369c2c9a)

[OpenNash Jobs](https://jobs.opennash.com/) / [Jiangsu Hengrui Medicine](https://jobs.opennash.com/companies/jiangsu-hengrui-medicine/) / 药化助理总监/副总监

## Job description

### 药化策略与分子设计
- 主导靶点药化可行性评估及从Hit到PCC的发现与优化全流程，基于SAR、DMPK及安全性数据迭代分子结构，确定临床前候选化合物。

### 项目全流程管理
- 制定研发计划与里程碑，统筹推进从立项到IND申报支持的全流程，负责合成路线规划、关键节点决策及风险管控。

### 跨部门协同与资源管理
- 联动生物、DMPK、药理、CMC及专利等部门推动项目交付；内外部CRO的进度跟踪、数据审阅与质量把控。

### 技术指导与团队建设
- 为组内成员提供实验设计、数据分析及问题解决的技术指导，组织技术分享与培训，营造开放高效的科研氛围，提升团队整体药化设计水平与凝聚力。

### 学历专业
- 药物化学、有机化学或相关专业博士学历。

### 工作经验
- 5年以上工业界新药研发经验，其中不少于3年作为药化项目负责人，有成功推进至PCC经验者优先。

### 技术能力
- 精通药物化学设计原则，能综合平衡活性、选择性、成药性与可开发性。

### 管理能力
- 具备优秀的跨学科沟通、资源协调、团队建设与人员培养能力。

### 其他
- 英文听说读写流利，有海外教育/工作背景优先。

### Job Title

Assistant Director, Medicinal Chemistry Position Level: L40 Assistant Director, leading a team of 3–5 people Job Responsibilities:

### Medicinal Chemistry Strategy and Molecular Design
- Lead target druggability assessment and the full discovery and optimization process from Hit to PCC; iterate molecular structures based on SAR, DMPK, and safety data to identify preclinical candidate compounds.

### Full-Cycle Project Management
- Develop research plans to ensure milestones delivery; coordinate and advance the full process from project initiation to IND filing support; responsible for synthetic route planning, key milestone decision-making, and risk management.

### Cross-Functional Collaboration and Resource Management
- Collaborate with biology, DMPK, pharmacology, CMC, and intellectual property departments to drive project delivery; track progress, review data, and ensure quality control for internal and external CROs.

### Technical Guidance and Team Building
- Provide technical guidance to team members in experimental design, data analysis, and problem-solving; organize technical sharing and training; foster an open and efficient research atmosphere; and enhance the team's overall medicinal chemistry design capabilities and cohesion.

### Education and Major
- PhD in medicinal chemistry, organic chemistry, or a related field.

### Work Experience
- More than 5 years of industry experience in new drug R&D, including no less than 3 years as a medicinal chemistry project leader; experience successfully advancing a project to PCC is preferred.

### Technical Capabilities
- Proficient in medicinal chemistry design principles; able to comprehensively balance potency, selectivity, drug-likeness, and developability.

### Management Capabilities
- Excellent cross-disciplinary communication, resource coordination, team building, and personnel development skills.

### Other
- Fluent in English listening, speaking, reading, and writing; overseas education/work background preferred.

## At a glance
- Posted by the employer: Sep 17, 2026
- First seen by OpenNash: Oct 11, 2026
- Last checked: Oct 18, 2026
- Listed for: 31 days
- Location: 中国 · 上海市[Apply on Jiangsu Hengrui Medicine’s careers site →](https://app.mokahr.com/social-recruitment/hengrui/145996#/job/cfc2809b-445f-4b62-933c-c4ff369c2c9a)

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