[Skip to main content](#main-content)

[ OpenNash ](https://opennash.com/) / [Jobs](https://jobs.opennash.com/) [ 01 Search jobs](https://jobs.opennash.com/search/)[ 02 Companies](https://jobs.opennash.com/explore/)[ 03 Hiring report](https://jobs.opennash.com/reports/hiring/)[ 04 AI assistants](https://jobs.opennash.com/connect/)[ 05 How it works](https://jobs.opennash.com/methodology/)

IBM · San Francisco, CA

# Digital Pharmaceutical Manufacturing & Enterprise Technology Lead

San Francisco, CA Manager or lead Healthcare & Clinical 

Listed on IBM’s official careers site. Posted November 6, 2026. Check that it is still open and apply there.
[Apply on IBM’s careers site →](https://ibm.dejobs.org/jobs/456A397E13E2462EAE085C9FFBE9F7E3/)

[OpenNash Jobs](https://jobs.opennash.com/) / [IBM](https://jobs.opennash.com/companies/ibm/) / Digital Pharmaceutical Manufacturing & Enterprise Technology Lead

## Job description

### Introduction

A career in IBM Consulting is built on long-term client relationships and close collaboration worldwide. You'll work with leading companies across industries, helping them shape their hybrid cloud and AI journeys. With support from our strategic partners, robust IBM technology, and Red Hat, you'll have the tools to drive meaningful change and accelerate client impact. At IBM Consulting, curiosity fuels success. You'll be encouraged to challenge the norm, explore new ideas, and create innovative solutions that deliver real results.

Our culture of growth and empathy focuses on your long-term career development while valuing your unique skills and experiences.

### Your role and responsibilities

Seeking a Digital Pharmaceutical Manufacturing & Enterprise Technology Lead senior technology executive and client business development leader to serve as a trusted advisor and the face of IBM to Pharma/Biotech manufacturing clients. The successful candidate brings 15+ years of experience leading enterprise-wide digital transformation in regulated pharmaceutical, biopharmaceutical, and biotech manufacturing environments.

The role partners with senior operations, quality, and technology leaders to align technology strategy. In this role, you are a seasoned pharma and biotech manufacturing consultant who pairs deep domain and technical expertise with executive presence. You communicate with clarity and authority, lead through influence, and are equally effective in a boardroom, a design workshop, or on the manufacturing floor. Clients see you as a partner who understands their science, their regulators, and their business.

Your responsibilities include:
- Shape the client's digital manufacturing vision. Define and execute AI-enabled digital manufacturing roadmaps that unify ERP, MES, LIMS, QMS, EHS, serialization, advanced planning, and shop-floor/edge systems into a connected, validated operating model governed by FDA and GMP requirements.
- Lead greenfield and brownfield transformation. Provide architectural leadership for new manufacturing facility buildouts and modernization of existing plants — spanning clinical and commercial operations and end-to-end systems integration.
- Modernize the technology foundation. Guide the transition to secure, resilient hybrid cloud architectures that support mission-critical, GxP-regulated operations without compromising data integrity or validated state.
- Advise at the sr. stakeholder level. Translate business and regulatory priorities into architectural vision, solution guidance, and investment-grade roadmaps that resonate with both technical and business audiences.
- Grow the relationship and the business. Originate, shape, and expand business opportunities — identifying where IBM capabilities create measurable client value and leading solutioning through to proposal.
- Build lasting trust. Establish and sustain strong relationships with the client's leadership, product owners, and cross-functional stakeholders, engaging credibly with both business and technology leaders. This job can be performed from anywhere in the U.S. Required technical and professional expertise

### Pharma/Biotech Manufacturing Operations
- Deep knowledge of pharma/biotech manufacturing processes — including batch management, tech transfer, and scale-up from clinical to commercial. Strong MES expertise; Preferred: hands-on experience with Körber PAS-X MES Suite or Rockwell PAS-X

### Quality Management in Regulated Industries
- Strong knowledge of end-to-end quality processes: deviations, CAPA, change control, investigations, batch disposition and release, supplier quality, audits/inspections, and Annual Product Quality Review (APQR)

### Product Lifecycle Management (PLM / PLK)
- Knowledge of PLM and PLK practices across formulation, specifications, bill of materials, and recipe management

### Regulatory Submissions & Quality Platforms
- Experience with pharmaceutical regulatory submission and lifecycle processes: eCTD submissions, post-approval variations, regulatory change impact assessment, and IDMP data standards.

### Preferred

experience with Veeva Vault RIM, including integration with manufacturing and quality systems
- Understanding of serialization and track-and-trace requirements

### GxP, Validation & Data Integrity
- Strong command of GxP regulations and computerized system validation (CSV)

### Enterprise & Shop-Floor Integration
- Experience architecting integrated landscapes across ERP (e.g., SAP S/4HANA), MES, LIMS, QMS, EHS, advanced planning and scheduling, historians, and OT/edge systems

### AI & Data Foundations
- Experience designing and delivering AI-driven manufacturing solutions, including establishing a foundational semantic data layer — encompassing ontologies, knowledge graphs, contextualized manufacturing data models, unified namespace, and data fabric patterns
- Manufacturing Domain Expert, Strong MES expertise; Preferred: hands-on experience with Körber PAS-X MES Suite, Understanding of serialization and track-and-trace requirements, GxP,

### Preferred technical and professional experience

Greenfield manufacturing facility buildouts experience is a big plus — experience spanning digital plant design, system selection, integration architecture, and commissioning/qualification/validation (C&Q/CQV) through operational readiness (strong plus) IBM is committed to creating a diverse environment and is proud to be an equal-opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender, gender identity or expression, sexual orientation, national origin, caste, genetics, pregnancy, disability, neurodivergence, age, veteran status, or other characteristics.

IBM is also committed to compliance with all fair employment practices regarding citizenship and immigration status.

## At a glance
- Posted by the employer: Nov 6, 2026
- First seen by OpenNash: Nov 9, 2026
- Last checked: Nov 9, 2026
- Listed for: 3 days
- Location: San Francisco, CA[Apply on IBM’s careers site →](https://ibm.dejobs.org/jobs/456A397E13E2462EAE085C9FFBE9F7E3/)

## More jobs at IBM

### [Forward Deployed AI Architect](https://jobs.opennash.com/companies/ibm/jobs/456a810d4d2d0bb43802/)

San Francisco, CA

### [Modern Data & Strategy Architect](https://jobs.opennash.com/companies/ibm/jobs/e829c7d88440fbff8893/)

San Francisco, CA

### [Healthcare BPaaS GTM & Delivery Lead](https://jobs.opennash.com/companies/ibm/jobs/ec3fa34e12dc0f79b27b/)

Houston, TX

### [Director, Engineering - Confluent](https://jobs.opennash.com/companies/ibm/jobs/3abc4c14c0dca541b8bb/)

Armonk, NY

### [ERP Business Systems Analyst](https://jobs.opennash.com/companies/ibm/jobs/f5cba5fe3a59dfec20d7/)

Herndon, VA

## Similar jobs at other companies

### [Chemical/Pharmaceutical, Quality Assurance (NIGHTS)](https://jobs.opennash.com/companies/cardinal-health/jobs/3820614d0455be80725d/)

Cardinal Health · Albuquerque, NM

### [Chemical/Pharmaceutical, Quality Assurance (NIGHTS)](https://jobs.opennash.com/companies/cardinal-health/jobs/0cb9ed94e070c715d79e/)

Cardinal Health · Denver, CO

### [Pharmaceutical Project Executive](https://jobs.opennash.com/companies/johnson-controls-international/jobs/f95dc7afe8def74d6c54/)

Johnson Controls International · Indianapolis-Indiana-United States of America

### [Process Engineer - Pharmaceutical Packaging](https://jobs.opennash.com/companies/thermo-fisher-scientific/jobs/7af8e381ed61b70b4c30/)

Thermo Fisher Scientific · Allentown, Pennsylvania, United States of America

### [Pharmaceutical Sales Representative - Brooklyn, NY](https://jobs.opennash.com/companies/gsk/jobs/983420d3f4179f41a7cd/)

GSK · Brooklyn, New York, United States of America

[Healthcare & Clinical jobs](/functions/healthcare-clinical/)

OpenNash lists jobs from employers’ own careers sites and does not handle applications.
Dates come from the employer where stated; “first seen” and “last checked” are our own observations.

[ OpenNash ](https://opennash.com/)

AI-native services firm that builds custom software and 24/7 AI agents.

OpenNash Jobs is an OpenNash Applied AI project.
[Book time with OpenNash](https://calendly.com/opennash/new-meeting?hide_gdpr_banner=1)

Jobs
- [Search jobs](https://jobs.opennash.com/search/)
- [Companies](https://jobs.opennash.com/explore/)
- [Hiring report](https://jobs.opennash.com/reports/hiring/)
- [AI assistants](https://jobs.opennash.com/connect/)
- [How it works](https://jobs.opennash.com/methodology/)

OpenNash
- [opennash.com](https://opennash.com/)
- [Services](https://opennash.com/ai-agent-consulting/)
- [OpenNash CX](https://opennash.com/cx/)
- [AI Tools](https://opennash.com/ai-tools/)
- [Blog](https://opennash.com/blog/)
- [About](https://opennash.com/about/)

Contact
- [hello@opennash.com](mailto:hello@opennash.com)

- [LinkedIn](https://www.linkedin.com/company/opennash)

- [Support](https://jobs.opennash.com/support/)

- [Privacy](https://jobs.opennash.com/privacy/)

- [Terms](https://jobs.opennash.com/terms/)

© 2026 OpenNash, Inc. Company names and public job postings belong to their respective owners. Employers control source availability and application decisions.