[Skip to main content](#main-content) [OpenNash Jobs](https://jobs.opennash.com/) [Hiring report](/reports/hiring/) · [All AstraZeneca jobs](https://jobs.opennash.com/companies/astrazeneca/) · [Search jobs](/search/) AstraZeneca · Boston, Massachusetts # Head of US Strategic Initiatives and Operations Boston, Massachusetts Executive Operations Listed on AstraZeneca’s official careers site. Listed as of October 18, 2026. Check that it is still open and apply there. [Apply on AstraZeneca’s careers site →](https://careers.astrazeneca.com/job/boston/head-of-us-strategic-initiatives-and-operations/43991/101628136512) [OpenNash Jobs](https://jobs.opennash.com/) / [AstraZeneca](https://jobs.opennash.com/companies/astrazeneca/) / Head of US Strategic Initiatives and Operations ## Job description ### This is what you will do The Head of Strategic Initiatives & Operations will report into the VP of US Value and Access. This position is responsible for owning initiatives that require cross-functional, above brand coordination, both internal and external to the US Value and Access organization. This role is based at Alexion’s Boston headquarters. You will be responsible for: Create executive-level narratives and recommendations for senior leadership endorsement and cross-functional alignment of key priorities Leading or setting up task forces to take on strategic initiatives, such as AI initiatives, launch ways of working, business review, etc. Assessing and informing the market access organization of new capabilities / innovation that can improve the efficiency and effectiveness of the US Value and Access organization Leads in the impact modeling of environmental shifts and marketplace dynamics on the Alexion portfolio of medicines Acting as the market access lead on cross-functional initiatives with teams outside of the US Value and Access organization (e.g. ### Strategic Account - Leads, sales organization, Patient Services, BOCE, etc.) - Ensure effective governance process and organize major meeting schedule for Market Access team Co-lead with VP Market Access development of annual operating plan (focus on FTE and project spend) - Lead all market access-wide internal meetings, training and compliance initiatives - Manage market access budget activities including working closely with Finance - Identify interdependencies and connections between departments and ensure integrated end-to-end visibility and alignment. You will need to have: - Bachelor’s Degree or the equivalent in Life Sciences, Business, or a related field - 10+ years of related and/or transferable experience in a biotech or pharma company - Ability to complete quantitative and qualitative analyses of complex business proposals - Strong understanding of relevant U.S. regulations and policies - Demonstrated ability to effectively communicate complex business challenges and data-driven recommendations to senior leaders - Knowledge of the US market access landscape as well as subject matter expertise of Market Access organizations We would prefer you to have: MBA or other advanced degree - Must have project management experience and excellent analytical, strategic thinking, creativity and problem-solving skills Expresses industry knowledge and acumen including Rare Disease experience - Strong communication skills and ability to work with cross-functional teams - Ability to work under pressure, in a fast-paced environment - Must exhibit strong leadership skills Advanced computer skills (Excel, Power Point and Microsoft Project) Date Posted 06-Oct-2026 Closing Date 11-Oct-2026 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form. ## At a glance - Posted by the employer: Not stated - First seen by OpenNash: Oct 11, 2026 - Last checked: Oct 18, 2026 - Listed for: 7 days - Location: Boston, Massachusetts[Apply on AstraZeneca’s careers site →](https://careers.astrazeneca.com/job/boston/head-of-us-strategic-initiatives-and-operations/43991/101628136512) ## More jobs at AstraZeneca ### [Administrative Coordinator](https://jobs.opennash.com/companies/astrazeneca/jobs/89c44f6195b25a9e97cf/) Boston, Massachusetts ### [Associate Director, CMC Lead](https://jobs.opennash.com/companies/astrazeneca/jobs/003df0b352289dba5fa3/) Boston, Massachusetts ### [Associate Director, External Quality](https://jobs.opennash.com/companies/astrazeneca/jobs/61a0dbffecb39638cb04/) Boston, Massachusetts ### [Associate Director, Incentive Compensation](https://jobs.opennash.com/companies/astrazeneca/jobs/bff36f031d66a3339115/) Boston, Massachusetts ### [Associate Director, Safety Scientist](https://jobs.opennash.com/companies/astrazeneca/jobs/ecc467cf008459258c0a/) Boston, Massachusetts ## Similar jobs at other companies ### [Specialist, CRM Strategic Initiatives](https://jobs.opennash.com/companies/macys/jobs/7a0d3f843954c5dbbc7c/) Macy's · New York, NY, United States ### [Control Management Strategic Initiatives - Vice President](https://jobs.opennash.com/companies/jpmorganchase/jobs/9c5fe3a6b01af0612680/) JPMorganChase · Plano, TX, United States ### [F-35 Strategic Initiatives Principal - Level 6](https://jobs.opennash.com/companies/lockheed-martin/jobs/7e0a04024f7af4a5a728/) Lockheed Martin · Fort Worth, TX ### [Head of Strategic Initiatives](https://jobs.opennash.com/companies/stifel-financial/jobs/2968a0b433b017f6f9ba/) Stifel Financial · Sherman Oaks, California ### [VP, Head of Program Management & Strategic Initiatives](https://jobs.opennash.com/companies/fidelity-national-information-fis/jobs/dce5602638d27afa6b29/) Fidelity National Information (FIS) · Jacksonville, FL, United States of America OpenNash lists jobs from employers’ own careers sites and does not handle applications. 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