[Skip to main content](#main-content) [OpenNash Jobs](https://jobs.opennash.com/) [Hiring report](/reports/hiring/) · [All AstraZeneca jobs](https://jobs.opennash.com/companies/astrazeneca/) · [Search jobs](/search/) AstraZeneca · Macclesfield, United Kingdom # Senior Scientist Process Engineer - Pharmaceutical Product Development Macclesfield, United Kingdom Full-time Senior individual contributor {'@type': 'MonetaryAmount', 'currency': '', 'value': {'@type': 'QuantitativeValue', 'unitText': ''}} Healthcare & Clinical Listed on AstraZeneca’s official careers site. Posted October 21, 2026. Check that it is still open and apply there. [Apply on AstraZeneca’s careers site →](https://careers.astrazeneca.com/job/macclesfield/senior-scientist-process-engineer-pharmaceutical-product-development/7684/102197137328) [OpenNash Jobs](https://jobs.opennash.com/) / [AstraZeneca](https://jobs.opennash.com/companies/astrazeneca/) / Senior Scientist Process Engineer - Pharmaceutical Product Development ## Job description ### Job Title Senior Scientist Process Engineer - Pharmaceutical Product Development Location: Macclesfield Salary: Competitive Introduction to role: Are you ready to turn cutting-edge science into dependable, scalable manufacturing that delivers medicines to patients sooner? Do you thrive at the bench and at the whiteboard, pairing experiments with models to make confident, high-impact decisions? Based in the UK, Macclesfield you will be a laboratory-based senior scientist who combines hands-on experimentation with modelling, simulation and digital tools to create robust processes for oral and parenteral drug products in late-stage development. You will join a cross-functional process technology and engineering team that sits at the interface of science and manufacturing. Here, your work will strengthen process understanding, shape development strategies and influence how new medicines are made at commercial scale. Can you see yourself designing critical experiments in the morning and using digital insights in the afternoon to steer the next wave of development? ### Accountabilities Process Design and Optimization: Lead the design, development and optimization of robust manufacturing processes for oral and parenteral drug products, ensuring long-term performance and patient needs are met. ### Experimental Process Understanding Design, execute and interpret laboratory studies to build deep process understanding and generate decision-enabling data. ### Scale-Up and Technology Transfer Contribute within cross-functional teams to develop, scale and transfer reliable commercial manufacturing processes for oral solid dosage forms and parenteral products. ### Modelling and Simulation Apply modelling, simulation and digital tools to guide experimental strategy, quantify risk and accelerate development timelines. ### Digital Enablement Champion and advance digital approaches that enhance pharmaceutical process development and strengthen data integrity and reuse. ### Data-Driven Collaboration Build strong partnerships with formulation scientists, engineers, modelling and simulation specialists, and manufacturing experts to solve complex technical challenges. ### Technical Planning and Delivery Independently plan and deliver technical activities to agreed timelines and quality standards, applying sound engineering judgement to interpret results and adapt strategies. ### Scientific Networking and Foresight Contribute to scientific and technology networks, maintaining awareness of emerging methods and technologies relevant to pharmaceutical product development. ### Essential Skills/Experience PhD in Chemical Engineering, Applied Physics or a related scientific discipline, or an MSc with significant industrial experience in pharmaceutical process development. Hands-on laboratory experience, including experimental design, data generation and interpretation to support process understanding and development. Demonstrated experience in pharmaceutical process development within CMC, including the design, development and optimisation of drug product manufacturing processes for oral solid dosage forms and/or parenteral products. Strong understanding of CMC regulatory requirements, with experience preparing regulatory documentation to support clinical development and/or marketing applications. Experience applying modelling, simulation and digital technologies to support process understanding, development and decision-making. Strong scientific problem-solving skills, with the ability to analyse data, interpret results, and make sound technical decisions. Strong collaboration and communication skills, with the ability to work effectively across multidisciplinary teams. Ability to work effectively in a global, cross-functional environment and build strong collaborative relationships across disciplines. Excellent written and spoken English. ### Desirable Skills/Experience Experience leading engineering work packages, process development activities or technology transfer projects within pharmaceutical development. Experience of commercial process development and technology transfer for new chemical entities. Experience of continuous processing in a pharmaceutical environment. Knowledge of GMP, Process Safety, Data Integrity and Change Control requirements. Experience working with automated manufacturing systems and digitalised process development environments. Experience working with CDMOs and outsourced development activities. Experience exploring or applying AI-enabled tools within pharmaceutical development. ### Why AstraZeneca Join a community where scientists, engineers and digital specialists work side by side to move molecules to medicines with pace and precision. You will influence how a diverse pipeline is developed and manufactured, from high-tech labs to modern production lines that apply lean thinking, automation and advanced analytics. Here, unexpected combinations of expertise come together to test bold ideas, learn fast and scale what works, all within a culture that values kindness alongside ambition. With strong investment, global reach and a clear focus on sustainability including ambitious goals to cut our environmental footprint, you will build skills for the future while contributing directly to therapies that change lives. ### Call to Action We are looking forward to your application not later than 1 November 2026. Date Posted 21-Oct-2026 Closing Date 01-Nov-2026 Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form. ## At a glance - Posted by the employer: Oct 21, 2026 - First seen by OpenNash: Oct 25, 2026 - Last checked: Oct 25, 2026 - Listed for: 4 days - Location: Macclesfield, United Kingdom - Employment type: Full-time - Pay: {'@type': 'MonetaryAmount', 'currency': '', 'value': {'@type': 'QuantitativeValue', 'unitText': ''}}[Apply on AstraZeneca’s careers site →](https://careers.astrazeneca.com/job/macclesfield/senior-scientist-process-engineer-pharmaceutical-product-development/7684/102197137328) ## Hiring at AstraZeneca - Open jobs: 853 - New in the last 7 days: 237 - Tracked since: Jul 16, 2026 [All AstraZeneca jobs](https://jobs.opennash.com/companies/astrazeneca/) · [Weekly hiring report](/reports/hiring/) ## More jobs at AstraZeneca ### [Audit Director, IT & Digital](https://jobs.opennash.com/companies/astrazeneca/jobs/8bf98fbec02d85e212af/) Macclesfield, United Kingdom ### [Pilot Plant Project Coordinator](https://jobs.opennash.com/companies/astrazeneca/jobs/5f4387d9d0c7eb400bec/) Macclesfield, United Kingdom ### [(Senior) Medical Science Liaison Specialist - CVRM - HCM](https://jobs.opennash.com/companies/astrazeneca/jobs/1fe223f641f65c9b492a/) Ho Chi Minh City, Ho Chi Minh, Vietnam ### [(Senior) Medical Science Liaison Specialist - R&I - HCM](https://jobs.opennash.com/companies/astrazeneca/jobs/28a81c12e9f774d9af1e/) Ho Chi Minh City, Ho Chi Minh, Vietnam ### [AI Researcher, Associate Director, AI for Clinical Development](https://jobs.opennash.com/companies/astrazeneca/jobs/111e65849036a87d48b2/) Barcelona, Spain ## Similar jobs at other companies ### [Principal Scientist, Early In-Process Analytics, Biotherapeutics Process Development, Pharmaceutical Sciences](https://jobs.opennash.com/companies/takeda-pharmaceutical/jobs/873d2fbd19bc01865c0d/) Takeda Pharmaceutical ### [Principal Scientist, Process Chemistry TSHO, Synthetic Molecule Process Development, Pharmaceutical Sciences, R&D](https://jobs.opennash.com/companies/takeda-pharmaceutical/jobs/4e62fea023a2a89ccd61/) Takeda Pharmaceutical ### [Sr. Process engineering -Peptides/Small molecule Scientist](https://jobs.opennash.com/companies/eli-lilly/jobs/4ab1eed72db120e91f02/) Eli Lilly · Hyderabad, Telangāna, India ### [Manufacturing Sciences, Process Scientist II](https://jobs.opennash.com/companies/thermo-fisher-scientific/jobs/90a48cd0cd903dcbd6fc/) Thermo Fisher Scientific · Monza, Monza e Brianza, Italy ### [(Senior) Scientist (F/M/D): Hybrid Modeling AND Process Simulation (80 TO 100%)](https://jobs.opennash.com/companies/abb/jobs/c83cadad23f5d86ccf06/) ABB · Mannheim, Baden-Wurttemberg, Germany OpenNash lists jobs from employers’ own careers sites and does not handle applications. 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