[Skip to main content](#main-content) [ OpenNash ](https://opennash.com/) / [Jobs](https://jobs.opennash.com/) [ 01 Search jobs](https://jobs.opennash.com/search/)[ 02 Companies](https://jobs.opennash.com/explore/)[ 03 Hiring report](https://jobs.opennash.com/reports/hiring/)[ 04 AI assistants](https://jobs.opennash.com/connect/)[ 05 How it works](https://jobs.opennash.com/methodology/) Amgen · Puerto Rico - Juncos, US # Manager Maintenance – AML6 Drug Substance (12 hrs./Night Shift) Puerto Rico - Juncos, US Full-time Manager or lead Skilled Trades & Maintenance Listed on Amgen’s official careers site. Posted October 28, 2026. Check that it is still open and apply there. [Apply on Amgen’s careers site →](https://amgen.wd1.myworkdayjobs.com/Careers/job/US---Puerto-Rico---Juncos/Manager-Maintenance---AML6-Drug-Substance--12-hrs-Night-Shift-_R-259428) [OpenNash Jobs](https://jobs.opennash.com/) / [Amgen](https://jobs.opennash.com/companies/amgen/) / Manager Maintenance – AML6 Drug Substance (12 hrs./Night Shift) ## Job description Career Category Maintenance ### Job Description Join Amgen’s Mission of Serving Patients At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. Amgen is advancing a broad and deep pipeline and portfolio of medicines to treat heart disease, obesity and obesity-related conditions, rare diseases, inflammatory conditions and cancer. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Manager Maintenance – AML6 Drug Substance (12 hrs./Night Shift) What you will do Let’s do this. Let’s change the world. In this vital role you will be responsible for the leadership and execution of maintenance activities in accordance to the production schedule and compliance requirements. You will assure process reliability by providing effective management of the Maintenance Program and associated resources. Converts the organization’s asset management strategy into workplace activities, provides technical expertise, strategic direction and management to a multi skilled maintenance work force from the AML6 Drug Substance Manufacturing Plant in a 12-hour non-standard shift operation. Specific responsibilities include but are not limited to: Support the development and execution of the Maintenance vision, strategy, and goals to advance a best-in-class Maintenance Organization. Lead, develop, and manage a team of Instrument and/or Maintenance Technicians, including workload prioritization, training, technical development, performance management, and quality of work. Lead corrective, preventive maintenance, and calibration programs to ensure timely, effective repairs and execution of planned maintenance activities in accordance with established targets, compliance requirements, and available maintenance windows. Drive maintenance planning and scheduling in partnership with Maintenance, Manufacturing, and Support areas to minimize operational impact and continuously improve the planning and scheduling process. Use the CMMS to document maintenance activities, maintain equipment and spare-parts records, prepare reports, analyze performance trends, and recommend or implement corrective actions. Develop, review, and maintain procedures, training materials, and job plans; provide technical guidance in accordance with applicable standards, codes, and best practices. Ensure a safe work environment by implementing safety programs and maintaining appropriate housekeeping practices within maintenance shops and operating areas. Manage Change Controls and CAPA requirements; support validation activities, deviation investigations, compliance audits, and Quality events. Lead maintenance continuous improvement initiatives using Lean/Six Sigma methodologies to improve reliability, efficiency, and maintenance execution. Support management of the maintenance section budget and expenses. Lead maintenance logistics and execution during planned plant slowdowns and shutdowns. Build and maintain effective working relationships with internal and external customers, contractors, and suppliers Support night and 12hrs non-standard shifts, including extended hours, as per business needs. What we expect of you We are all different! Yet, we all use our unique contributions to serve patients. The Mgr Maintenance professional we seek is a collaborative people leader with these qualifications. ### Basic Qualifications Doctorate degree or Master’s degree and 3 years of Maintenance and/or Engineering support experience or Bachelor’s degree and 5 years of Maintenance and/or Engineering support experience or Associate’s degree and 10 years of Maintenance and/or Engineering support experience or High school diploma / GED and 12 years of Maintenance and/or Engineering support experience In addition to meeting at least one of the above requirements, you must have previous managerial experience directly managing people and/or leadership experience leading teams, projects, programs, or directing the allocation of resources. Your managerial experience may run concurrently with the required technical experience referenced above. ### Preferred Qualifications Bachelor’s or master’s degree in Life Sciences and/or Engineering. Hands-on experience providing troubleshooting support. Knowledge of biotechnology equipment and processes used in Drug Substance operations, including bioreactors, chromatography, and centrifugation. Demonstrated initiative to help the team take a proactive rather than reactive approach. Progressive technical and managerial experience in Maintenance and/or Engineering within a regulated manufacturing environment. Strong knowledge of industrial equipment and facilities, applicable compliance regulations, maintenance programs, reliability practices, and predictive/preventive maintenance. Experience with reliability practices, and familiarity with validation process and cGMP documentation. Demonstrated leadership, team-building, staff relations, coaching, mentoring, and employee counseling skills. Experience operating with a high degree of organizational skill, urgency, negotiation, collaboration, and the ability to prioritize multiple tasks in a fast-paced, changing, 24/7 operation. Lean/Six Sigma experience and a demonstrated continuous improvement mindset; Green Belt, Black Belt, or other Continuous Improvement certifications are preferred. Strong written and verbal communication skills in English and Spanish, including the ability to prepare high-quality reports and deliver presentations to multiple organizational levels. Advanced computer skills, including proficiency in the Microsoft Office Suite and working knowledge of CMMS systems. Availability to support a non-standard shift organization, as per business needs. What you can expect of us As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being. In addition to the base salary, Amgen offers a Total Rewards - Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including: A comprehensive employee benefits package, including a Retirement and Savings - Plan with generous company contributions, group medical, dental & vision coverage, and life & disability insurance. A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan. Stock-based long-term incentives. Award-winning time-off plans and an annual site shutdown Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies. Apply now and make a lasting impact with the Amgen team. careers.amgen.com In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information. Sponsorship Sponsorship for this role is not guaranteed. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease. Amgen is an Equal Opportunity employer. We make all employment decisions without regard to race, color, religion, sex or any other characteristic protected by applicable law. We provide reasonable accommodations to applicants and employees with disabilities, consistent with legal requirements. Please contact us to request accommodation.. ## At a glance - Posted by the employer: Oct 28, 2026 - First seen by OpenNash: Nov 1, 2026 - Last checked: Nov 1, 2026 - Listed for: 4 days - Location: Puerto Rico - Juncos, US - Employment type: Full-time[Apply on Amgen’s careers site →](https://amgen.wd1.myworkdayjobs.com/Careers/job/US---Puerto-Rico---Juncos/Manager-Maintenance---AML6-Drug-Substance--12-hrs-Night-Shift-_R-259428) ## Hiring at Amgen - Open jobs: 1,989 - New in the last 7 days: After two weekly collections - Tracked since: Jul 10, 2026 [All Amgen jobs](https://jobs.opennash.com/companies/amgen/) · [Weekly hiring report](/reports/hiring/) ## More jobs at Amgen ### [Engineer - Packaging](https://jobs.opennash.com/companies/amgen/jobs/b10fa4b0104619404c24/) Puerto Rico - Juncos, US ### [Engineer AML 7 - Process Engineering (Night Shift)](https://jobs.opennash.com/companies/amgen/jobs/ca94cf5b20e0323a8d20/) Puerto Rico - Juncos, US ### [Senior Director Engineering – AML14 Drug Product](https://jobs.opennash.com/companies/amgen/jobs/ef21eacea45e501c35b4/) Puerto Rico - Juncos, US ### [Senior Director Human Resources - Puerto Rico Site Lead](https://jobs.opennash.com/companies/amgen/jobs/ddbe96288fd49eb4e9ab/) Puerto Rico - Juncos, US ### [Sr. Manufacturing Systems Engineer (Automation Engineer)](https://jobs.opennash.com/companies/amgen/jobs/11e2459a18fd9727cbb7/) Puerto Rico - Juncos, US ## Similar jobs at other companies ### [Drug Substance MSAT Scientist II](https://jobs.opennash.com/companies/thermo-fisher-scientific/jobs/09b4689c02357707277d/) Thermo Fisher Scientific · Plainville, Massachusetts, United States of America ### [Director, Vaccines Drug Substance Commercialization - Upstream](https://jobs.opennash.com/companies/merck-co/jobs/c7e20d6ed94f231e5ad8/) Merck & Co. · USA - Pennsylvania - West Point ### [Site MS&T Head SMO - Drug Substance](https://jobs.opennash.com/companies/novartis/jobs/cb441a0f6d1754e49201/) Novartis · Morrisville ### [Director/Principal Scientist, Biologics Drug Substance Commercialization (BDSC)](https://jobs.opennash.com/companies/merck-co/jobs/6167c6a7407bca6d877a/) Merck & Co. · USA - Pennsylvania - West Point ### [MS&T Senior Scientist - Small Molecule Drug Substance](https://jobs.opennash.com/companies/vertex-pharmaceuticals/jobs/470d789e03f5b78387b6/) Vertex Pharmaceuticals · Boston, MA OpenNash lists jobs from employers’ own careers sites and does not handle applications. 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