[Skip to main content](#main-content) [OpenNash Jobs](https://jobs.opennash.com/) [Hiring report](/reports/hiring/) · [All Alnylam Pharmaceuticals jobs](https://jobs.opennash.com/companies/alnylam-pharmaceuticals/) · [Search jobs](/search/) Alnylam Pharmaceuticals · United States # Director, Head of Incentive Compensation & Execution Excellence United States Executive $204,000 — $276,000 Executive & Management Listed on Alnylam Pharmaceuticals’s official careers site. Posted November 2, 2026. Check that it is still open and apply there. [Apply on Alnylam Pharmaceuticals’s careers site →](https://job-boards.greenhouse.io/alnylampharmaceuticals/jobs/4470510009) [OpenNash Jobs](https://jobs.opennash.com/) / [Alnylam Pharmaceuticals](https://jobs.opennash.com/companies/alnylam-pharmaceuticals/) / Director, Head of Incentive Compensation & Execution Excellence ## Job description ### Overview The Director of Sales Execution & Enablement is responsible for designing, operationalizing, and driving adoption of incentive compensation programs and field enablement initiatives that improve execution, behavior change, and measurable performance outcomes. This role sits at the intersection of incentive compensation, field enablement, and execution excellence, ensuring that compensation plans and enablement efforts translate into consistent field execution and KPI attainment. The role partners closely with Sales Leadership, Finance, HR, Training, and Field Enablement to align incentives, tools, and coaching with company priorities and frontline execution. ### Key Responsibilities Incentive Compensation Strategy & Execution - Design and manage incentive compensation plans that drive desired field behaviors, execution excellence, and strategic priorities - Translate business goals into clearly defined measures of success, including quantifiable targets and performance metrics - Partner with Finance, HR, Legal, Compliance, and Sales to ensure incentive compensation plans are compliant, scalable, and financially sound - Lead annual and quarterly compensation planning cycles, including scenario modeling and performance forecasting - Own compensation plan communication, field readiness, and ongoing interpretation to ensure clarity and adoption - Ensure enablement efforts tied to incentive compensation are measurable, behavior based, and linked to KPIs - Provide strategic oversight of all incentive and bonus programs to ensure they are executable, motivating, compliant, and fiscally responsible - Lead the accurate and timely execution of incentive compensation plans, including payout calculations, documentation, and governance - Define and drive short and long term solutions for incentive compensation administration, enabling scalable capabilities, tools, and technology to support a growing and increasingly complex field organization; partner with Commercial Enablement, IT, and other internal teams to deliver these solutions - Provide strategic leadership for the Incentive Compensation (IC) and President’s Club (PC) programs in close partnership with field leadership, HR, and Finance - Make data driven recommendations on compensation design and goal setting methodologies, informed by modeling, testing, and validation - Conduct regular IC health checks (e.g., goal attainment and payout distributions, advantaged/disadvantaged segments) to ensure plans perform in line with design objectives - Develop clear, effective materials to communicate plan designs to field teams, including design documents, IC statements, ranking reports, and payout estimators - Define and operationalize leading and lagging KPIs that measure execution quality, adoption, and outcomes - Work closely with Advanced Analytics team to build dashboards and reporting that provide actionable insights at the rep, manager, and leadership levels - Monitor performance trends to identify risks, opportunities, and coaching needs - Translate insights into targeted actions for leaders and frontline managers Enable frontline managers with coaching frameworks, performance insights, and incentive literacy - Partner with Sales Leadership and training to embed coaching into operating rhythms, e.g., QBRs - Support managers in diagnosing performance issues and reinforcing behaviors tied to incentives and enablement - Promote a culture of continuous improvement, accountability, and data driven coaching Qualifications: Bachelor’s degree or better - 10+ years of experience in Incentive Compensation, Field Enablement, and / or Commercial Effectiveness - Proven experience designing and operationalizing incentive compensation plans tied to behavior and execution - Strong understanding of sales motions, frontline execution, and manager led coaching Experience defining and using KPIs to drive adoption and performance change - Ability to translate data into actionable insights Exceptional stakeholder management and communication skills Experience leading, coaching, and developing dynamic teams of high performing individuals. Capable & proven presenter to executive audiences. Track record of delivering solutions with excellent attention to detail, accuracy, and derived value. High sense of urgency, balanced with focus on quality & process. Project management skills with demonstrated ability to lead multiple projects & priorities. Ability to travel for key external & internal meetings as needed (Role requires ~10% overnight travel). About Alnylam We are the leader in RNAi therapeutics – a revolutionary approach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possible and are just at the beginning of what’s possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, where an authentic, inclusive culture and breakthrough thinking fuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer. Before applying, please review Alnylam's ⁠Candidate Privacy Notice regarding how Alnylam handles Personal Data you provide with your application for employment. #LI-SS1 #LI-Remote The pay range below reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam’s robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: [https://www.alnylam.com/careers](https://www.alnylam.com/careers) U.S. Pay Range $204,000 — $276,000 USD ## At a glance - Posted by the employer: Nov 2, 2026 - First seen by OpenNash: Nov 3, 2026 - Last checked: Nov 3, 2026 - Listed for: 1 day - Location: United States - Pay: $204,000 — $276,000[Apply on Alnylam Pharmaceuticals’s careers site →](https://job-boards.greenhouse.io/alnylampharmaceuticals/jobs/4470510009) ## Hiring at Alnylam Pharmaceuticals - Open jobs: 102 - New in the last 7 days: After two weekly collections - Tracked since: Oct 20, 2026 [All Alnylam Pharmaceuticals jobs](https://jobs.opennash.com/companies/alnylam-pharmaceuticals/) · [Weekly hiring report](/reports/hiring/) ## More jobs at Alnylam Pharmaceuticals ### [Associate Director, Field Operations](https://jobs.opennash.com/companies/alnylam-pharmaceuticals/jobs/c21412362ea763dc9a2b/) United States ### [Associate Director, Field Reimbursement](https://jobs.opennash.com/companies/alnylam-pharmaceuticals/jobs/f4e5156f36706bae0f3e/) United States ### [Health Systems Director](https://jobs.opennash.com/companies/alnylam-pharmaceuticals/jobs/ca170d412894c9c20645/) United States ### [Regional Business Director, TTR - South Central (Atlanta, AL, LA, AR, MS)](https://jobs.opennash.com/companies/alnylam-pharmaceuticals/jobs/57f8bacc8ea6412db930/) United States ### [Senior Director, US Strategic Accounts](https://jobs.opennash.com/companies/alnylam-pharmaceuticals/jobs/b91e2527ef6c83b7c0a8/) United States ## Similar jobs at other companies ### [Engineering Manager - Incentive Compensation](https://jobs.opennash.com/companies/thrivent-financial/jobs/3653618ccf66e495e955/) Thrivent Financial · United States ### [Sr Incentive Consultant](https://jobs.opennash.com/companies/citizens-financial-group/jobs/ae7e8082dd0f5311d0c9/) Citizens Financial Group · United States ### [Associate Director, Incentive Compensation](https://jobs.opennash.com/companies/astrazeneca/jobs/bff36f031d66a3339115/) AstraZeneca · Boston, Massachusetts ### [Director, Incentive Compensation, Sales Planning, & Launches](https://jobs.opennash.com/companies/biogen-idec/jobs/c1c5a8a36c7c5e86e6e2/) Biogen · Cambridge, MA ### [Sr. Director, US Sales Incentive Compensation](https://jobs.opennash.com/companies/astrazeneca/jobs/29b78300a1d3265ea935/) AstraZeneca · Boston, Massachusetts OpenNash lists jobs from employers’ own careers sites and does not handle applications. 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