[Skip to main content](#main-content) [OpenNash Jobs](https://jobs.opennash.com/) [Hiring report](/reports/hiring/) · [All AbbVie jobs](https://jobs.opennash.com/companies/abbvie/) · [Search jobs](/search/) AbbVie · Waltham, MA # Principal Research Scientist I – Analytical Development – PDST – Late-Stage Process Analytics Waltham, MA Full-time Senior individual contributor Data & Analytics Listed on AbbVie’s official careers site. Posted October 13, 2026. Check that it is still open and apply there. [Apply on AbbVie’s careers site →](https://careers.abbvie.com/en/job/principal-research-scientist-i-analytical-development-pdst-late-stage-process-analytics-in-waltham-ma-jid-34349) [OpenNash Jobs](https://jobs.opennash.com/) / [AbbVie](https://jobs.opennash.com/companies/abbvie/) / Principal Research Scientist I – Analytical Development – PDST – Late-Stage Process Analytics ## Job description Company Description About AbbVie AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube. ### Job Description The Principal Scientist I will be an integral part of the Process Analytics team in the Operations – Product Development Science and Technology – Biologics division. The role involves leading analytical activities within a high-throughput testing group supporting biologics products with a focus on advancing AbbVie’s late-stage clinical programs. This position calls for an individual with a strong technical analytical background, demonstrated leadership and organizational skills and the ability to effectively communicate and work cross-functionally. ### Responsibilities Lead analytical activities within a high-throughput testing group supporting biologics process development for late-stage programs. Serve as the subject matter expert for separation-based methods, including HPLC and capillary electrophoresis. Evaluate and select effective fit for purpose analytical technologies and methods to meet process development needs. Provide expertise and support for method development, execution, and troubleshooting. Provide direct technical guidance and oversight to scientists executing sample testing with hands on lab support when needed. Partner with process development SMEs for interpretation and understanding of analytical data. Oversee sample testing schedule and prioritization; drive timely delivery of high-quality testing results. Support implementation of automation and high-throughput experimentation workflows. Drive continuous improvement initiatives to enhance lab efficiency and capability. Mentor, train and supervise junior scientists. ### Qualifications PhD in chemistry, biology, biochemistry, chemical engineering, or related technical discipline with 6+ years of relevant professional experience working in analytical development or process analytics; MS degree with minimum of 10+ years of relevant experience. Proven experience leading analytical development activities for biologics development, including mAbs, multi-specifics, antibody-drug conjugates, and fusion proteins. Hands on method development experience in protein and impurity analysis techniques such as HPLC, capillary electrophoresis, and other relevant methods for biologics required. Experience with mass spectrometry and ELISA is a plus. Previous experience with automation is a plus. Highly organized with ability to multitask and drive efficient workflows. Ability to think critically and demonstrate troubleshooting and problem-solving skills. Strong people leadership skills and demonstrated ability to foster an engaging, inclusive and collaborative team environment. Direct people management experience required. Excellent communication and interpersonal skills. Ability to work effectively across functions, anticipating and addressing overall program development needs. An independent, self-motivated, proactive individual who thrives in a fast-paced team environment. Additional Information Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​ The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future. ​ We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.​ This job is eligible to participate in our long-term incentive programs. ### Note No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.​ AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled. US & Puerto Rico only - to learn more, visit [https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html](https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html) US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more: [https://www.abbvie.com/join-us/reasonable-accommodations.html](https://www.abbvie.com/join-us/reasonable-accommodations.html) ## At a glance - Posted by the employer: Oct 13, 2026 - First seen by OpenNash: Oct 18, 2026 - Last checked: Oct 18, 2026 - Listed for: 5 days - Location: Waltham, MA - Employment type: Full-time[Apply on AbbVie’s careers site →](https://careers.abbvie.com/en/job/principal-research-scientist-i-analytical-development-pdst-late-stage-process-analytics-in-waltham-ma-jid-34349) ## More jobs at AbbVie ### [Associate Director / Principal Research Scientist II, Precision Medicine Immunology](https://jobs.opennash.com/companies/abbvie/jobs/7cdd9c32e79ee898a17f/) Waltham, MA ### [Executive Medical Director Oncology Early Development In Waltham Ma Jid 33110](https://jobs.opennash.com/companies/abbvie/jobs/6ee2e314bc179c30dc42/) Waltham, MA ### [QA Specialist (Batch Record Reviewer)](https://jobs.opennash.com/companies/abbvie/jobs/28ba2d8df81012201e16/) Waltham, MA ### [Scientific Director, Precision Medicine - Immunology](https://jobs.opennash.com/companies/abbvie/jobs/bb12b7fb7477c4e8601b/) Waltham, MA ### [Senior Counsel, U.S. Policy Legal](https://jobs.opennash.com/companies/abbvie/jobs/8f0a57a8109d71bec20a/) Waltham, MA ## Similar jobs at other companies ### [FSP Associate Research Scientist: QC Strategy & Analytical Sciences](https://jobs.opennash.com/companies/thermo-fisher-scientific/jobs/541c609382a4e1522844/) Thermo Fisher Scientific · New Brunswick, New Jersey, United States of America ### [Analytical Development Scientist (HPLC)](https://jobs.opennash.com/companies/thermo-fisher-scientific/jobs/79b7d54f975cbd327d38/) Thermo Fisher Scientific · Bedford, Massachusetts, United States of America ### [Scientist- Analytical Research and Development](https://jobs.opennash.com/companies/pfizer/jobs/1e00f49f87257a34a07e/) Pfizer · United States - Connecticut - Groton ### [Research Scientist 2](https://jobs.opennash.com/companies/humana/jobs/ec75b9eedca849c2c7ce/) Humana · Remote, Nationwide ### [Analytical Science and Technology Principal Scientist](https://jobs.opennash.com/companies/vertex-pharmaceuticals/jobs/5593554760db9aa271b0/) Vertex Pharmaceuticals · Boston, MA OpenNash lists jobs from employers’ own careers sites and does not handle applications. Dates come from the employer where stated; “first seen” and “last checked” are our own observations. OpenNash Jobs · Official listings with dates and links to the employer. [Weekly hiring report](/reports/hiring/) · [Methodology](/methodology/)